Extended Spectrum B-Lactamases among Clinical Isolates of Enterobacteriaceae Ssp.: Prevalence and Susceptibility Pattern at A Tertiary Care Hospital
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 2
Abstract
The purpose of this study was to know prevalence and susceptibility pattern of extended spectrum β-lactamases(ESBLs) at our tertiary care centre. A total of 660 non-repetitive clinical isolates of Enterobacteriaceae obtained from various clinical samples of which isolates that exhibited intermediate/ resistance to third generation cephalosporins were screened to detect ESBL producers by double disk synergy test. ESBLs were confirmed by phenotypic confirmatory test and E-test ESBL strips. Among 660 Enterobacteriaceae isolates, 125(18.9%) of which were ESBL producers. E.coli 53.6% was the largest group followed by K. pneumoniae 32.8% and all other species together comprised 13.6%. Continued monitoring of drug resistance is necessary in clinical settings for proper disease management.
Authors and Affiliations
Sanjeev Kumar, Sudhir Kumar Mehra, R. C. Kanta
Keywords
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