Extensively drug resistant tuberculosis (XDR-TB): A potential threat
Journal Title: Journal of Basic and Clinical Pharmacy - Year 2011, Vol 2, Issue 1
Abstract
Emergence of extensively drug resistant tuberculosis (XDR-TB) has been reported by more than 55 countries. XDR-TB is considered as untreatable and highly fatal disease. In developing countries like India, number of cases of multi-drug resistant tuberculosis (MDR-TB) and XDR-TB are increasing. Emergence of resistance to Isoniazid and Rifampicin, the two most effective and well tolerated agents, coupled with resistance to second line agents pose limited treatment options for XDR-TB. The present minireview provides information about the seriousness of XDR-TB and the drugs available for its treatment. Although considered a fatal disorder, judicious use of combination of drugs, retaining their antimycobacterial activity, can improve the clinical outcome of XDR-TB. Only such an approach can provide some hope for the patients of XDR-TB.
Authors and Affiliations
Anaga Marwar, Nanadal , Ivvala Shaker, Hemraz Palawan, Ranjith S. , GokulShankar
Keywords
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