Extracranial and intracranial arterial stenoocclusive disease in acute ischemic stroke patients: A study from north India - Evaluation with MR angiography

Journal Title: Indian Journal of Neurosciences - Year 2017, Vol 3, Issue 1

Abstract

Background: Asian, African, and Hispanic ancestry are at higher risk of intracranial atherosclerosis. In North America, extracranial carotid stenosis remains the most common vascular lesion in Caucasian. However the studies in Indian population are lacking. Aims: The study was done to evaluate extracranial and intracranial arterial stenoocclusive diseases in acute ischemic stroke with MR angiography. Material and Methods: This prospective study was conducted on 50 subjects of ischemic stroke. A thorough clinical examination, history of risk factors, routine baseline investigations for stroke, Brain CT/ MRI, and MRA study of extracranial and intracranial vessels (three-dimensional time-of-flight technique) were done in all patients. Results: Twenty two (44%) have abnormal MRA with significant steno-occlusive lesions. The intracranial stenosis was more common than extracranial stenosis in our population and was statistically significant (p value < 0.05). The intracranial stenosis was more common in younger age (age < 60 years), diabetics and female sex while extracranial stenosis was more common in old age (age > 60 years), ischemic heart disease and male patients. Conclusion: The intracranial stenosis was more common than extracranial stenosis in our studied population. The present study confirms racial difference between Indians and whites in location of lesion in cerebrovascular steno-occlusive. Further large scale population based studies are needed.

Authors and Affiliations

Trilochan Srivastava, Sujit Kumar, Vijay Sardana, Piyush Ojha, Dilip Maheshwari, Bharat Bhushan

Keywords

Related Articles

Lipomyelomeningocele: Controversies in management

Management of lipomyelomeningocele is one of the most discussed and controversial topic in recent years Till date there is no consensus on most appropriate mode of management for lipomyelomeningocele particularly in asym...

Serum Calcium and Magnesium Levels do not correlate with Severity of Major Depressive Disorder

Major Depressive Disorder (MDD) is one of the leading cause of morbidity amongst psychiatric illness. Pathophysiology of MDD is still a matter of research and not much is known about it. Although, it is certain that neu...

A prospective study of correlation of gestational age, birth weight and perinatal risk factors with various cranial ultra sound findings in high risk neonates

Background: CUS plays an important role in assessing neurological prognosis of these high risk infants. This study was conducted to assess the correlation of gestational age, birth weight and perinatal factors with vario...

Level of stress and its contributing factors among first year medical students

Background: Stress in medical students is a well documented fact that cannot be denied and more or less it is system oriented. Through a minimal amount of stress is essential to ignite a healthy and competitive spirit, b...

A 6 week prospective randomized comparative study of metabolic adverse effects of Risperidone and Iloperidone in patients with schizophrenia

Introduction: The antipsychotics Risperidone and Iloperidone are the two different benzisoxazole derivatives that are structurally different and metabolized differently. Risperidone has moderate effects on metabolic para...

Download PDF file
  • EP ID EP309532
  • DOI 10.18231/2455-8451.2017.0005
  • Views 75
  • Downloads 0

How To Cite

Trilochan Srivastava, Sujit Kumar, Vijay Sardana, Piyush Ojha, Dilip Maheshwari, Bharat Bhushan (2017). Extracranial and intracranial arterial stenoocclusive disease in acute ischemic stroke patients: A study from north India - Evaluation with MR angiography. Indian Journal of Neurosciences, 3(1), 21-25. https://europub.co.uk/articles/-A-309532