Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion

Journal Title: International Journal of Bioprinting - Year 2017, Vol 3, Issue 1

Abstract

Tissue engineering approaches have been adopted to address challenges in osteochondral tissue regeneration. Single phase scaffolds, which consist of only one single material throughout the whole structure, have been used extensively in these tissue engineering approaches. However, a single phase scaffold is insufficient in providing all the properties required for regeneration and repair of osteochondral defects. Biphasic scaffolds with two distinct phases of titanium/type 1 collagen and titanium-tantalum/type 1 collagen were developed for the first time using selective laser melting and collagen infiltration. Observation of the biphasic scaffolds demonstrated continuous interface between the two phases and mechanical characterization of the metallic scaffolds support the feasibility of the newly developed scaffolds for tissue engineering in osteochondral defects.

Authors and Affiliations

Swee Leong Sing, Shuai Wang, Shweta Agarwala, Florencia Edith Wiria, Thi Mai Hoa Ha and Wai Yee Yeong

Keywords

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  • EP ID EP678662
  • DOI -
  • Views 162
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How To Cite

Swee Leong Sing, Shuai Wang, Shweta Agarwala, Florencia Edith Wiria, Thi Mai Hoa Ha and Wai Yee Yeong (2017). Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion. International Journal of Bioprinting, 3(1), -. https://europub.co.uk/articles/-A-678662