FACTOR STRUCTURE OF PARAMETERS OF EX VIVO MUSCLE GASTROCNEMIUS MEDI-ALIS ISOMETRIC CONTRACTION IN LABORATORY RATS WITH ACUTE PELVIC LIMB ISCHEMIA

Abstract

Two factors that affect the own muscle contractile ability in isometric mode in rats with acute shim ischemia (1, 3 and 6 h), reproduced by compression of artery femoralis occlusion, were found by the application of method of analysis of the principal components, method of orthogonal rotation of factors in two-dimensional space varimax and scree plot criterion. Tetanic contraction of the muscle was recorded by the strain gauge method for 60 minutes. The muscle was irritated through rectangular pulses (voltage 2 V, 0.2 ms duration, frequency 50 Hz), which were formed in 12 cyclical stimulus patterns 3 sec duration and 5 min period. It was found that the first factor was loaded by variables that characterize the biomechanical muscle contraction properties: muscle strength, the time to peak tension, fusion index, muscle contraction and half-relaxation time, muscle strength increase during tetanic contraction and its reduction during tetanic half-relaxation, and the second factor - muscle fatigue index. The conclusion about the dependence of own ischemic muscle contractile ability in rats on variables of the first factor and influence of fatigue as a secondary factor was made.

Authors and Affiliations

O. A. Melnychuk, S. Ye. Shvaiko

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  • EP ID EP308720
  • DOI -
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How To Cite

O. A. Melnychuk, S. Ye. Shvaiko (2016). FACTOR STRUCTURE OF PARAMETERS OF EX VIVO MUSCLE GASTROCNEMIUS MEDI-ALIS ISOMETRIC CONTRACTION IN LABORATORY RATS WITH ACUTE PELVIC LIMB ISCHEMIA. Вісник Одеського національного університету. Біологія, 21(1), 155-163. https://europub.co.uk/articles/-A-308720