FACTOR STRUCTURE OF PARAMETERS OF EX VIVO MUSCLE GASTROCNEMIUS MEDI-ALIS ISOMETRIC CONTRACTION IN LABORATORY RATS WITH ACUTE PELVIC LIMB ISCHEMIA
Journal Title: Вісник Одеського національного університету. Біологія - Year 2016, Vol 21, Issue 1
Abstract
Two factors that affect the own muscle contractile ability in isometric mode in rats with acute shim ischemia (1, 3 and 6 h), reproduced by compression of artery femoralis occlusion, were found by the application of method of analysis of the principal components, method of orthogonal rotation of factors in two-dimensional space varimax and scree plot criterion. Tetanic contraction of the muscle was recorded by the strain gauge method for 60 minutes. The muscle was irritated through rectangular pulses (voltage 2 V, 0.2 ms duration, frequency 50 Hz), which were formed in 12 cyclical stimulus patterns 3 sec duration and 5 min period. It was found that the first factor was loaded by variables that characterize the biomechanical muscle contraction properties: muscle strength, the time to peak tension, fusion index, muscle contraction and half-relaxation time, muscle strength increase during tetanic contraction and its reduction during tetanic half-relaxation, and the second factor - muscle fatigue index. The conclusion about the dependence of own ischemic muscle contractile ability in rats on variables of the first factor and influence of fatigue as a secondary factor was made.
Authors and Affiliations
O. A. Melnychuk, S. Ye. Shvaiko
Keywords
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