FACTORS AFFECTING MORTALITY AND MORBIDITY OF PEPTIC ULCER PERFORATION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 43
Abstract
BACKGROUND Objectives- Peptic Ulcer Disease (PUD) refers to the underlying tendency to develop mucosal ulcers at sites that are exposed to peptic juice (acid and pepsin). Among abdominal emergencies, perforations of peptic ulcer are third in frequencies; acute appendicitis and acute intestinal obstruction being more common. Prompt recognition of the condition is very important and only by early diagnosis and treatment it is possible to reduce the mortality. This study was mainly conducted to assess the risk factors affecting mortality and morbidity in peptic ulcer perforation. MATERIALS AND METHODS This is a case series study of 60 cases operated for peptic ulcer perforation admitted to Chigateri General Hospital and Bapuji Hospital, attached to J. J. M. Medical College, Davangere from June 2009 to May 2011. A detailed history of suspected patients of peptic ulcer perforation regarding age, sex, previous use of NSAIDs, smoking and other associated illnesses was taken. Post-operative complications were assessed. The results were discussed and analysed for significance with available published literature. RESULTS Peptic ulcer perforation was common in the age group of 30 - 50 years with mean age of 44 years. Elderly patients (≥ 65 years) had increased morbidity (p-value 0.02) and mortality (p-value < 0.001). Peptic ulcer perforation was common in males than females in ratio of 9:1. Regular ingestion of NSAIDs and/or steroids was not an important risk factor in causation of peptic ulcer perforation. Smoking (58.3%) and alcohol beverage consumption (53.3%) were commonly seen in patients with peptic ulcer perforation. CONCLUSION Perforated peptic ulcer disease is emerging as a frequent cause of acute abdomen in South India. The perforation is common between age group of 30 - 50 years. It is more common in males. The duration of perforation more than 24 hours and presence of shock on admission is associated with increased morbidity and mortality in patients with peptic ulcer perforation. Early diagnosis and prompt management of shock and septicaemia is important for better prognosis of patients.
Authors and Affiliations
Sudhir Suresh Bhat, Avinash Patil
Keywords
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- EP ID EP214520
- DOI 10.14260/Jemds/2017/734
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