Factors affecting the immunogenicity of E. coli O78 vaccine in chickens
Journal Title: Journal of Veterinary Medical Research - Year 2019, Vol 26, Issue
Abstract
Bacterial disease still has serious problem in the intensive poultry production. In the recent years, particular concern has been raised by high incidence of poultry infections by E. coli. Analyses of antibacterial properties of essential oils have been carried out by range of researches. This experiment aimed to study the effect of immunomodulators on the immunogenicity of vaccine E. coli O78. In this study 250 broiler chickens were used. They were divided into 5 separated groups all groups vaccinated with E. coli O78 cebel coarse spray vaccine, except control group, 2 groups treated with immunomodulators, 3 groups challenged with untyped E. coli strain, all chickens housed in separated anavar. First group was control, 2nd group was vaccinated only, 3rd group was vaccinated and challenged, 4th group was vaccinated and received immunomodulators and 5th group was vaccinated, received immunomodulators and challenged. All chickens were observed daily food consumption, weight gained mortality rate, lesion, bioavailability, and weekly collected blood samples from 2-5 birds. The results were summarized as follows; immunomodulators have positive effect on B.W.G, decreased mortality and morbidity rate. The challenge enhanced the effect of E. coli O78 vaccine and there was marked improvement in bioavailability, B.W.G and immune defense against bacterial and respiratory diseases. Also, immunomodulators increased immunogenicity against bacterial disease through enhancing immune response system, and had synergistic effect with vaccination against E. coli.
Authors and Affiliations
El-Seedy , F. R. , Aml Mokhtar, Eman Khalifa, Sara Sayed
Characterization of Variant Strain of Newcastle Disease Virus in Egypt
During 2005, velogenic Newcastle disease virus (NDV) caused a major outbreak among commercial broiler chicken in Egypt. The outbreak raised concerns regarding the protective immunity of commercially available vaccines fo...
Some pharmacological studies of cephradine in broilers
The pharmacokinetic aspects of cephradine were studied after intravenous (IV), intramuscular (IM), subcutaneous (SC) and oral administration of a single dose of 50 mg kg-1 b.wt. in chickens. Tissue distribution and resid...
Organochlorine pesticides residues in butter, olive oils and corn oils
Dietary fat and oil is important for many body processes. The present investigation was carried out to determine the concentrations of organochlorine pesticides in butter, olive and corn oil. A total of 125 samples (75 b...
Vancomycin resistance among methicillin-resistant Staphylococcus aureus isolates from animal milk
Staphylococcus aureus(S. aureus) is a major cause of mastitis in dairy animals and a serious pathogen affecting human health. The current study was designed to investigate the extent of S.aureus in milk samples collected...
Characterization of autofluorescence in normal and necrosed muscles in chickens
The histopathological diagnosis of muscle necrosis and hyalinosis frequently poses considerable difficulty and has a contradictory diagnosis. The present study described the morphologic features of nine clinically affect...