Factors Associated With Glycemic Control among Type 2 Diabetes Patients Attending Mathari National Teaching Hospital, Nairobi Kenya
Journal Title: Journal of Endocrinology and Diabetes - Year 2016, Vol 3, Issue 6
Abstract
Introduction: Type 2 Diabetes mellitus is chronic metabolic disorder characterized by hyperglycemia resulting from insulin secretion, insulin action, or both and accounts for over 95% cases globally. Uncontrolled diabetes may result to complications (retinopathy, nephropathy, neuropathy leading to amputations, stroke, heart attack and sexual dysfunction), glycated hemoglobin below 7.0% is recommended for good prognosis.The study determined factors associated with glycemic control, among T2DM patient attending Mathari National and Referral Hospital Nairobi, Kenya. Method: A descriptive cross sectional study design was used systematic random sampling technique to select 149 study subjects T2DM patients. Quantitative data was collected using a structured questionnaire for socioeconomic and patients practice. Key informants interviews and Focus group discussions collected qualitative data. Blood samples were drawn for Hba1c, lipid profiles, blood sugar and urine for microalbumin Creatinine Ratio analysis. Data was analyzed using Statistical Package for Social Scientists version 20(SPSS). Descriptive analysis was used to summarize the data. Associations between variables were tested using Chi Square statistics. Qualitative data was analyzed thematically after translation and transcription. Difference between parameter estimates were deemed statistically significant at p<0.05. Results: The mean age of study participants was 54 years and a total of 122(81.6%) out of 149 participants had poor glycemic control with a mean HBA1C of 9.1, 90.6% having elevated FBS, 37.6% with elevated T-Chol and 60.4% having high LDL levels. Twenty four percent had moderately increased UACR while 11.4% had severely increased UACR. Gender (OR3.029, 95%CI: 1.287–7.129, p=0.010), FBS (OR=8.14, 95%CI; 2.541-26.0810, p=0.001) and using drugs for other co-morbidities OR=2.519, 95%CI; 1.009-6.288, p=0.035) were associated with glycemic control. Conclusion: There is a high burden of poor glycemic control among T2DM patients in Mathari National Teaching and Referral Hospital especially women. With the burden of diabetes increasing, emphasis on diabetes awareness and education to fill in the practice gap in glycemic control. Managing FBS and detecting other co-morbidities like, hypertension, kidney problems and dyslipidemia to be done routinely to prevent development of complications.
Authors and Affiliations
Ngoyo James Nduati, Karanja Simon, Njenga Eva, Muthami Lawrence
Keywords
Related Articles
- EP ID EP333703
- DOI 10.15226/2374-6890/3/6/00162
- Views 89
- Downloads 0
Effect of Beta - Blockers on Insulin Resistance in Patients with Hypertension and Metabolic Syndrome after 6 Months of Treatment
Background:For years the use of beta-blockers in patients with metabolic syndrome has been limited due to the negative impact of non-selective beta - blockers on carbohydrate and lipid metabolism. Aim:We studied antihyp...
Iatrogenic Milk Alkali Syndrome in a Patient Recovering from Acute Renal Failure
We describe a 49 year old morbidly obese man with iatrogenic milk alkali syndrome. He presented with sepsis resulting in acute renal failure with resultant hyperphosphatemia treated with high dose calcium carbonate. As h...
Thyroid-Induced Toxicity of Check-Point Inhibitors Immunotherapy in the Treatment of Advanced Non-Small Cell Lung Cancer
Immunotherapy represents a new strategy in the fight against cancer diseases based on the key role that immune system plays to identify and destroy foreign or abnormal cells in the body, including tumor cells. Nowadays,...
Strategies of Hyperglycemia Management among Patients with Diabetic Nephropathy, Renal Impairment, Hypertension and Lipid Disorders
Diabetic nephropathy, a microvascular complication, usually starts by the development of incipient nephropathy (microalbuminuria), then proteinuria, reduced glomerular filtration rate and finally renal impairment or Chro...
Observational Study of the Tunisian Diabetic Patients' Profile during the Fasting of the Holy Month of Ramadan
Aims: To analyze the profile of patients with Type 1 Diabete Mellitus (T1DM) and Type 2 Diabetes Mellitus (T2DM) fasting during Ramadan. Methods: Descriptive observational epidemiological study in T1DM and T2DM diabetes...