Factors associated with the levels of N- amino terminal prohormone brain natriuretic peptid in hypertensive population
Journal Title: Dicle Tıp Dergisi - Year 2014, Vol 41, Issue 2
Abstract
Objectives: In this study we ınvestigated that which the factors affecting the level of N- amino terminal prohormone brain natriuretic peptid (NT-pro BNP) in hypertensive population. Methods: A total of 309 hypertensive patients (mean age 50.5 ± 10.7, 49.2% male) were enrolled into the study. Lower group was defined as NT-pro BNP 60 pg/dl or low, high group was defined as NT-pro BNP 60 pg/dl higher. The patients with secondary hypertensive, heart failure, coronary artery disease, valvular diseases, chronic renal failure (serum creatinine >1.5 mg/dl, blood urea nitrogen>30 mg/dl) and chronic obstructive pulmonary disease were excluded from the study. Results: Left ventricular mass index, 24-h systolic blood pressure, day systolic blood pressure, night systolic blood pressure and night diastolic blood pressure higher in high group than lower group. In stepwise linear regression analysis, a significant relation was found between sex, left ventricular mass index, age, night systolic blood pressure and higher NT-pro BNP levels (R²=0.236, ß= -0.258, P<0.001, ß=0.185, P=0.006, ß=0.174, P=0.010, ß=0.160, p=0.015 respectively). Conclusion: Age, gender, left ventricle mass index and night systolic blood pressure were found as independent predictive factors on NT-pro BNP in hypertensive patients. Key words: NT-pro BNP, hypertension, Turkish society
Authors and Affiliations
Hamdi Püşüroğlu , Mehmet Erturk, Özgür Akgül, İsmail Bolat, Emre Akkaya, Aydın Yıldırım
Keywords
Related Articles
- EP ID EP152541
- DOI 10.5798/diclemedj.0921.2014.02.0421
- Views 94
- Downloads 0
Adölesan amatör futbolcularda görülen spina iliaka anterior ve superior avulsiyon kırıklarının konservatif tedavisi: İki olgu sunumu
Spina İliaka Anterior İnferior (SİAİ) ve Spina İliaka Anterior Superior (SİAS) avülsiyon kırıkları pelvisin nadir görülen yaralanmalarındandır. Genelde sporcularda ve futbol oynarken şut çekme sırasında gerçekleştiği düş...
Fetal intra-abdominal umbilikal ven varisi: Olgu sunumu
Umbilikal ven varisi, umbilikal damarların nadir bir anomalisidir. Bu makalede; 25 yaşında, fetal intraabdominal ekstrahepatik umblikal ven varisi tespit edilen gebe sunulmuştur. Gelişme geriliği oluşan olgunun gebeli...
Association of hypoxia inducible factor 1 (HIF-1) and paraoxonase enzyme in lung cancer cell lines
Objective: In this study, it was aimed to investigate that PON2, in hypoxia and normoxia in relation to HIF-1α transcription factor that has a role in tumour angiogenesis. Hypoxia inducible factor 1 alpha (HIF-1α) is a t...
A rare cause of bilateral and recurrent facial palsy: Melkersson-Rosenthal sendromu
Melkersson-Rosenthal syndrome is a granulomatous disease which is characterized by the triad of recurrent peripheral facial palsy, orofacial edema, and fissured tongue. In this article we presented one case who, since c...
Nadir görülen bir olguda zor havayolu yönetimi: Singnati
Konjenital izole mandibula ve maksilla füzyonu nadir görülen fakat neonatal dönemde havayolunun sağlanmasında anesteziste önemli zorluklar çıkarabilen bir anomalidir. Havayolunun korunması ve intraoperatif yönetimi zor...