Falsely Elevated Acetaminophen Levels in the Setting of Hyperbilirubinemia
Journal Title: Journal of Advances in Internal Medicine - Year 2013, Vol 2, Issue 4
Abstract
A 51-year-old male with a history of heavy alcohol abuse presented with alcoholic hepatitis and acute renal failure. Although he denied acetaminophen (APAP) ingestion, he was found to have elevated APAP levels that persisted and actually increased despite treatment with N-acetylcysteine. Review of the literature reveals that falsely elevated APAP levels may rarely occur with patients suffering from liver failure and felt to be related to severe hyperbilirubinemia. Interpretation of APAP levels in patients with severe liver disease and hyperbilirubinemia may be difficult and lead to diagnostic and therapeutic confusion.
Authors and Affiliations
Parth J. Parekh| Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA, United States, Thomas J. Manser*| Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA, United States
Keywords
Related Articles
- EP ID EP4773
- DOI http://dx.doi.org/10.3126/jaim.v2i2.8782
- Views 369
- Downloads 20
ALLELOPATHIC EFFECTS OF ANACARDIUM OCCIDENTALE LINN OF TERENGGANU AND KELANTAN ON GROWTH OF MAIZE AND CUCUMBER
A study was conducted on Anacardium occidentale Linn. (Cashew) from Terengganu and Kelantan states of Malaysia, with the aim to determine the allelopathic effects of leaf and root extracts on the growth of bioassay plant...
FIELD WATER MANAGEMENT AND N-RATES TO SAVE WATER AND CONTROL IRON TOXICITY IN LOWLAND RICE
Field trial was conducted in 2009 and 2010 to evaluate water and nitrogen management on concentration of iron as it affects yield of lowland rice in the National Cereals Research Institute (NCRI) research fields in Bida,...
Accuracy of commonly used equations for estimating glomerular filtration rate in Nepalese population
Introduction - Estimation of glomerular filtration is of utmost importance in clinical practice. Various equations have been developed in different populations based on serum creatinine. These equations have not yet been...
Expressions of HPV 16-E6 in esophageal carcinoma and its clinical significance
Aim: The aim of the study was to explore the association between HPV16-E6 protein and esophageal squamous cell carcinoma. Methods: SP immunohistochemical method was used to examine the expression of HPV 16-E6 in 50 cases...
Six Minute Walk Test as a Monitoring tool in Chronic Obstructive Pulmonary Disease on Pulmonary Rehabilitation
Background and Aims- The six minute walk test is widely used as an outcome measure in pulmonary rehabilitation programs. The objective of this study is to report the magnitude of change in the six minute walk test with t...