Familial Recurrent Hydatidiform Moles: A rare case report
Journal Title: Medical Science and Discovery - Year 2014, Vol 1, Issue 3
Abstract
Recurrent hydatidiform moles (RHM) are described as the being of at least two molar pregnancies in the same patient. It is very rare. NLPR7 mutations are found high rate in patients with RHM. KHDC3L is the second responsible gene for RHM. In this paper, we present an interesting case of a familial RHM. Here, we have discussed the genetic counseling to be given to a patient who had been diagnosed as hydatidiform mole in her two previous pregnancies and whose sister had a history of four consecutive molar pregnancies. Because rate of NLPR7 mutation is high in individuals with recurrent molar pregnancy, patients should be recommended to have NLRP7 gene sequence analysis in the first place. If no mutation is detected in this gene, KHDC3l gene sequence analysis should be carried out
Authors and Affiliations
Fatma Eskicioglu, Isin Kaya, Esra Bahar Gur, Guluzar Arzu Turan
Keywords
Related Articles
- EP ID EP520339
- DOI -
- Views 67
- Downloads 0
The evaluation of diagnostic performance of some enzymes for diagnosis and detection of breast cancer by ROC curve
Objective: In this study, it was aimed to examine the performance of Arylesterase (ARE), Paraoxonase-1 (PON-1) and Adenosine deaminase (ADA) enzymes to identify cancer patients and their stages with ROC curve in serum sa...
Delayed organophosphate - induced polyneuropathy
Introduction: Intoxication with organophosphate compounds used for pest control is common in Turkey. Organophosphate intoxication may occur during agricultural spraying, transport of organophosphate compounds, or domesti...
Complexion of Boric Acid with 2-Deoxy-D-glucose (DG) as a novel boron carrier for BNCT
Objective: Boron neutron capture therapy (BNCT) is an intensive research area for cancer researchers. Especially the side effects and inabilities of conventional therapies in some cases, directs researchers to find out...
Aqueous garlic extract protects against sepsis induced toxicity in pulmonary and ileal tissues
Objective: Based on the potent antioxidant effects of aqueous garlic extract (AGE), the present study was designed to characterize the potential of AGE to modify blood coagulation parameters as well as and pulmonary and...
Effects of radio-frequency radiation on the permeability of blood-brain barrier
Health concerns have been a raised after the enormous increase in the use of mobile phones and related base stations throughout the world. In spite of extensive increase in the studies of biological effects of mobile pho...