Features of lymphocyte phenotyping in patients with activated recurrent herpetic infection of the first/second type and reproductive system disorders
Journal Title: Міжнародний ендокринологічний журнал - Year 2017, Vol 13, Issue 1
Abstract
The aim of the study was an analysis of the features of changes in lymphocyte subpopulation according to the data of immunography in patients with a recrudescent herpetic infection and reproductive violations. Materials and methods. The peculiarities of lymphocyte phenotyping were studied in 120 patients with activated recurrent herpetic infection of the first/second type (herpes simplex virus (HSV) 1/2), among whom 63 patients were diagnosed with infertility. Results. An increase in the level of killer cells was detected: CD16+/56+ (NK-cells) — in moderately recurrent infection (1–5 relapses within one year) and CD3+/8+ (T-suppressor/killer cells) — in frequently recurrent infection (6 or more episodes during the year). Conclusions. In infertile patients with recurrent HSV 1/2 infection, there has been observed a deficit of cells with suppressive activity: CD4+CD25+CD127– (regulatory T-cells) lymphocytes and CD3+/8+ (T-suppressor/killer cells) lymphocytes.
Authors and Affiliations
T. V. Shmyga, V. Yu. Gayevska
Keywords
Related Articles
- EP ID EP176195
- DOI 10.22141/2224-0721.13.1.2017.96759
- Views 39
- Downloads 0
Clinical experience of using herbal medicinal product Glucemedin in the comprehensive treatment of patients with type 2 diabetes mellitus
Background. The current task of treating patients with type 2 diabetes mellitus and dyslipoproteinemia is the analysis of efficiency of the combination of standard hypoglycemic agents with phytotherapeutic drugs, but inf...
The effectiveness of methylcobalamin in the complex treatment of diabetic peripheral neuropathy
Background. Diabetic neuropathy is the most common complication of diabetes mellitus (DM), found in 30–90 % of patients. The relevance of the study is due to the prevalence of diabetic neuropathy, as well as assessing th...
Diabetes Mellitus Type 2: Choice of Sulfonylurea Preparation Taking into Account Patient’s Eating Behavior
.
The Many Faces of Glimepiride: on the Question of Interchangeability of Oral Hypoglycemic Agents
The article presents a literature review on the use of glimepiride while treating patients with diabetes mellitus. Characteristics of generic drugs of glimepiride are provided.
Parameters of stimulation electroneuromyography in patients with primary hypothyroidism
Background. The purpose of the work is to identify the parameters of stimulation electroneuromyography (ENMG) in patients with primary hypothyroidism against the background of autoimmune thyroiditis and postoperative hyp...