Features of pahogocytic activity of monocytes and neutrophils in patients with obesity and ankylosinig spondylitis depending on HLA B27 gene carrier
Journal Title: Міжнародний ендокринологічний журнал - Year 2017, Vol 13, Issue 3
Abstract
Background. Ankylosing spondylitis (AS) is a widespread pathology all over the world. The AS prevalence in different countries ranges from 0.2 to 2 %. Usually the disease debuts at the age of 20–40 years, men suffer from this pathology 6–9 times more often than women. Materials and methods. We observed 68 patients with acute stage. The general laboratory and AS-specific testing were done for all patents, namely clinical blood analysis with leucogram (%, g/l), ESR, C-reactive protein, proteingram, for HIV carrier, for HCV and HBV specific antibodies and HLA B27 carrie. Results. AS patients with HLAB27 antigene had enhanced spontaneous and physiologic output of neutrophils and physiologic output of monocytes. Conclusions. Oxidative output can serve as an early predictor of autoimunne process in human.
Authors and Affiliations
V. Yu. Hayevska
Keywords
Related Articles
- EP ID EP212786
- DOI 10.22141/2224-0721.13.3.2017.104122
- Views 64
- Downloads 0
Dynamics of Endothelial Function Impairment in Patients with Initial Poor Compensation of Type 2 Diabetes Mellitus in Correction of Hypertension with Angiotensin II Receptor Antagonists during a year
The purpose of this study is to determine the dynamics of endothelial dysfunction intensity in patients with poor compensation of type 2 diabetes mellitus and hypertension treating with angiotensin II receptor antagonist...
Indicators of the quality of life in women with Graves’ disease after radioactive iodine treatment
Background. The purpose of the research was to evaluate the quality of life in women with Graves’ disease after radioactive iodine therapy. Materials and methods. We have examined 79 women with Graves’ disease after rad...
The Phenomenon of Ischemic Preconditioning: the Effect of Glucose Imbalance and Antidiabetic Therapy
.
Functional Foods in Complex Treatment of Patients with Metabolic Syndrome
Functional foods are intended for a systematic daily consumption and have a regulating effect on physiological functions, biochemical reactions and psychosocial behavior due to the normalization of microecological status...
Advantages of the combined therapy with metformin and glimepiride in patients with type 2 diabetes mellitus
The use of glimepiride in the therapy of type 2 diabetes mellitus (DM) fewer stimulates the pancreas, keeping its resource, and does not result in hyperinsulinemia, and also provides the highest profile of safety at the...