A novel way to induce coronary hyperaemia

Coronary angiography and measurement of fractional flow reserve (FFR) are used for anatomical and functional assessment of coronary stenoses. The achievement of maximal coronary hyperaemia is crucial for an accurate calc...

Wpływ betuliny i 28-0-propynoilobetuliny na proliferację i apoptozę ludzkich komórek czerniaka linii G-361

Seladin-1/DHCR24: A key protein of cell homeostasis and cholesterol biosynthesis

Seladin-1 is a multifunctional protein encoded by DHCR24 gene and due to its enzymatic, antioxidant, and anti-apoptotic activities, it is considered as neuroprotective agent. Seladin-1 was identified as a gene down-regul...

The phenomenon of vitamin D

The receptor of vitamin D (VDR) is present in most non-skeletal human cells, suggesting its role beyond the bone and calcium metabolism. The relationship between vitamin D and the respiratory tract is a consequence of it...

Molecular mechanisms regulating metastasis of cancer cells with special emphasis on rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a malignant tumor of soft tissue derived from embryonic mesenchymal and/or neuroectodermal tissues. It is most often associated with other genetic syndromes such as Li-Fraumeni or Bechwith-Wiede...