Fetal goiter diagnosed on routine ultrasonographic assessment

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Fetal goiter diagnosed on routine ultrasonographic assessment – case report

Journal Title: Postępy Nauk Medycznych - Year 2015, Vol 28, Issue 12

Abstract

Fetal goiter is a rare condition usually caused by maternal Graves’ disease andtransplacental passage of thyroid stimulating antibodies or treatment with antithyroiddrugs, lithium, amiodarone or Lugol’s solution. Occasionally fetal goiter may becaused by congenital disorders in thyroid hormone synthesis. The prompt diagnosisand treatment is needed because fetal goiter is always accompanied by fetal thyroiddysfunction: hyper- or hypothyroidism – impairment of intellectual and somaticdevelopment may be the final consequence of the both. Here we present the caseof fetal goiter which was diagnosed on routine ultrasonographic assessment on the23rd week of gestation. The mother, 20-year old healthy woman was euthyroid andnegative for anti-TSH receptor antibodies. She did not take any medicines except forprenatal multivitamins containing 200 µg of iodine per tablet. The analysis of parenteraldata and TSH, fT4, fT3 concentrations from umbilical cord sampling led to thediagnosis of hypothyroid fetal goiter probably dyshormonogenetic. Treatment withl-thyroxine given intraamniotically and into umbilical vein was successfully undertaken.The patient is still under observation.

Authors and Affiliations

Małgorzata Gietka-Czernel, Marzena Dębska, Piotr Kretowicz, Romuald Dębski

Keywords

fetal goiter Hypothyroidism L-thyroxine treatment

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EP ID EP77383
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