Firm Yellowish Nodule on the Face of a 7-year-Old Child: What is Your Diagnosis?
Journal Title: Journal of Dermatology Research - Year 2020, Vol 1, Issue 1
Abstract
A 7 year old girl presented at our clinic with a 3 months history of cutanuous nodule on her face, which had gradually increased in size, non painless and pruritic. The dermatological examination revealed a 2 cm size firm erythematosis nodule, yellowish in the center, on the mental region. There was no mucosal involvement. The general physical examination was normal, with no signs of lymph node enlargement. Dermoscopy showed yellowish homogeneous areas in the center of the lesion, whereas, in the outer part, was a milky-red area, traversed by large telangiectatic vessels on a red-orange background. Histology revealed a normal epidermis, in the dermis, a nappe of cellular populations, made up of large, macrophagic-looking cells, with image of phagocytosis of lymphoid cells, was noted. The rest of the dermis showed dense inflammatory infiltrates, composed of neutrophils, plasma cells, lymphocytes and histiocytes. A phenomenon of emperipolesis was clearly defined. Immunohistochemical staining revealed that the histiocytes were strongly positive for S100 protein, weakly positive for CD68 and negative for CD1a. Cell blood count, liver and kidney function test, chest x-ray and abdominal ultrasonography were all normal (Fig. 1-3).
Authors and Affiliations
Dahhouki Sara, Bennani Mounia, Douhi Zakia, Elloudi Sara, Baybay Hanane, Mernissi Fatima Zahra, Fadel Reda, Kamal Dounia, Tahiri Layla, Hammas Naoual
Keywords
Related Articles
- EP ID EP699030
- DOI http://dx.doi.org/10.46889/JDR.2020.1104
- Views 74
- Downloads 0
Oral Clarithromycin Therapy for Perioral Dermatitis in Children: A Retrospective Case-series Study
Background: Effective treatments for pediatric periorificial dermatitis are limited. We assessed the clinical utility of oral Clarithromycin (CLR) in pediatric patients with periorificial dermatitis. Methods and Findi...
Efficacy and Tolerability of an Advance Face Night Cream in Reducing Facial Pigmentation and Wrinkles in Women
Background: The efficacy and tolerance of an Advance Face Night Cream in reducing facial pigmentation and wrinkles in women was evaluated. Methods: This was a monocentric, single-group, comparative, open-label study i...
A Case of Pseudochromohidrosis Cured with Oral Erythromycin and Topical Clindamycin
Apocrine chromohidrosis and eccrine pseudochromohidrosis are both rare skin presentations. In case of former patient presents with coloured sweats in apocrine distributions usually axilla, breast etc., while later pres...
Superficial Acral Fibromyxoma (SAF): A Case Report
Superficial Acral Fibromyxoma (SAFM) is a benign soft tissue tumor characterized by the presence of stellate and spindle-shaped cells arranged in a storiform and fascicular pattern. This tumor is relatively rare, benign...
Update Aetiopathogenesis and Treatment of Psoriasis: A Literature Review
Background: Psoriasis is a very common skin condition that is caused by an immune system problem. T-cells, dendritic cells, macrophages and neutrophils all play a role in the proliferation of keratinocytes. Several genet...