Fish intake and risk of prostate cancer
Journal Title: Advances in Hygiene and Experimental Medicine - Year 2014, Vol 68, Issue
Abstract
The aim of the study was to present the current state of knowledge concerning the relationship between the consumption of fish as materials rich in long chain polyunsaturated fatty acids (LC PUFA) omega-3, and the risk of prostate cancer. Many scientific reports confirm the health benefits from the consumption of fish and protective properties of LC PUFA omega-3 in relation to prostate cancer. However, there are reports that indicate a relationship of the high consumption of PUFA with the risk of prostate cancer. The way of processing and preservation of the fish, and other factors not included in previous studies, could have some importance in the etiology of this disease. High susceptibility of PUFA to oxidation changes and the technological fish processing (smoking, high-temperature cooking methods) contribute to the formation of many compounds, such as polycyclic aromatic hydrocarbons and heterocyclic amines – which may influence the formation of cancers – including prostate cancer. It is necessary to ensure an adequate amount of LC PUFA omega-3 in the diet through the consumption of proper quality fish and fish oils. Particular attention should be paid to the high susceptibility of PUFA to the oxidative processes, and the method of processing, preservation and storage of fish. Also pollution from the environment can significantly reduce the impact of health benefits of PUFA and fish, and even be the cause of cancers, including prostate cancer. Further research in this area should be more targeted to assess the impact of nutritional factors for the development of such tumors.
Authors and Affiliations
Ewa Dybkowska, Franciszek Świderski, Bożena Waszkiewicz-Robak
Keywords
Related Articles
- EP ID EP67497
- DOI -
- Views 150
- Downloads 0
Katelicydyny i defensyny w regulacji aktywności przeciwdrobnoustrojowej komórek tucznych
Katelicydyny i defensyny, należące do grupy peptydów przeciwdrobnoustrojowych, to cząsteczki efektorowe będące jednym z najstarszych ewolucyjnie mechanizmów obronnych. Wykazują głównie działanie przeciwbakteryjne, skiero...
Systemic and local mechanisms leading to cachexia in cancer
Cachexia is a multifactorial syndrome of atrophy of skeletal muscle and adipose tissue, resulting in progressive loss of body weight associated with low quality of life and poor prognosis in cancer. Studies on experiment...
Ogólnoustrojowe i miejscowe mechanizmy prowadzące do kacheksji w chorobach nowotworowych
Kacheksja to wieloczynnikowy zespół zaniku mięśni szkieletowych i tkanki tłuszczowej, powodujący postępującą utratę masy ciała, związany ze złym rokowaniem w chorobie nowotworowej. Badania przeprowadzone na zwierzęcych m...
Autophagy and BNIP3 protein in tumorogenesis
Autophagy is a process necessary for maintaining cell homeostasis in physiological conditions, as well as during certain stresses like nutrients or oxygen deprivation. Autophagy also plays an essential role in tumorigene...
Pentraxins – their importance in pathogenesis of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease, whose main pathomechanism is attributed to the disturbed apoptotic process and dysfunction of the immune cells, leading to the accumulation of undegraded cellu...