FLASH CHROMATOGRAPHY: AN OVERVIEW
Journal Title: Int J of Pharm Res & Analy - Year 2014, Vol 4, Issue 3
Abstract
Flash chromatography is a rapid purification technique used to purify compounds of wide ranging polarity; often reaction mixtures, where the target (synthesized) molecule must be separated from excess reagents and reaction by-products. It is an established technique that can have a very positive impact on productivity in the pharmaceutical research and development chemistry laboratory . Finding the optimal conditions for a normal phase or reverse phase Flash-LC separation can be a laborious process. The aim of this work was to develop a screening system to enable automated, rapid and reliable method development for preparative Flash chromatography.
Authors and Affiliations
S. Shalini , A. Ajitha , V. Uma Maheshwara Rao
Keywords
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