Flavonol glycosides with insecticidal activity from methanol extract of Annona mucosa leave
Journal Title: Trends in Phytochemical Research - Year 2019, Vol 3, Issue 4
Abstract
Three flavonoids, quercetin 3-O-β-D-glucoside (1), quercetin 3-O-α-D-arabinoside (2) and kaempferol 3-O-β-D-galactoside (3) were isolated from the methanol leaf extract of Annona mucosa. Their structures were determined using physical and spectroscopic methods. compound 1 showed the highest activity against both S. zeamais and P. truncatus with LC50 values of 20.891 μg/ml and 22.241μg/ml, respectively though lower than the activity of deltamethrine a commercial insecticide used as a positive control. Compounds 2 and 3 gave moderate toxicities with LC50 values of 21.745 μg/ml and 24.926 μg/ml for compound 2 and 29.260μg/ml and 24.241μg/ml for compound 3 when tested against S. zeamais and P. truncates, respectively. compounds 1, 2 and 3 were also tested for anti-feedant activities against S. zeamais and P. truncatus and they exhibited interesting results. The activities were concentration dependent, increasing with increase in concentration. Quercetin 3-O-β-D-glucoside (1) showed the highest activities with AFI50 values 14.856 µg/ml and 16.79 µg/ml against S. zeamais and P. truncatus respectively (Figure 3). This actvity was close to but lower than the activity of azadirachtin a commercial antifeedant that had an activity of AFI50 of 12.146 µg/ml and 12.432 µg/ml against S. zeamais and P. truncates, respectively. Compounds 2 and 3 also exhibited relatively high antifeedant activities with values of AFI50 values 17.257µg/ml and AFI50 19.965µg/ml for compound 2 while values of AFI50 21.599 µg/ml and 20.149 µg/ml were obtained for compound 3 respectively, when tested against S. zeamais and P. truncatus respectively.
Authors and Affiliations
Albert Mulianga Makenzi; Lawrence Onyango Arot Manguro; Philip Okinda Owuor; Sylvia Awino Opiyo
Keywords
Related Articles
- EP ID EP680654
- DOI -
- Views 129
- Downloads 0
Genetic variability of agronomic traits and biodiversity in the genus Ocimum
The present study was performed to explore genetic and chemotypic variability among five Ocimum species. Genotypes were evaluated from pooled data over three locations for two consecutive years (2007-2009). High genotypi...
Optimization of extraction methods for total polyphenolic compounds obtained from rhizomes of Zingiber officinale
In an alternative medicine, aqueous extracts and decoctions of a ginger root (Ginger –Zingiber officinale Roscoe L., Ginger family – Zingiber aceae) are used as antibacterial, diaphoretic, analgesic, anti-emetic, anti-in...
Phytochemical quantification, in vitro antioxidant and antidiabetic potentials of methanol and dichloromethane extracts of Triclisia subcordata (Oliv) leaves
Triclisia subcordata (Oliv) is a useful medicinal plant for the treatments of several diseases in South West, Nigeria. The methanol and dichloromethane extracts from the plant were investigated for the presence of phytoc...
In-vitro alpha amylase and alpha glucosidase inhibitory potential of leaf hexane, ethyl acetate and methanol fractions of Pterocarpus soyauxii Taub
Diabetes mellitus is a critical clinical condition characterized by hyperglycemia in which an accelerated amount of glucose circulates in the blood plasma. This work attempts to evaluate the α-amylase and α-glucosidase i...
Bioactive essential oils from the Cameroonian rain forest: A review - Part II.
Eighty-nine essential oil analyses carried out on Cameroonian plant material by gas chromatography are reviewed, and structures of sixty one main oil compounds are presented. Plant samples had been collected all over the...