FLOWCYTOMETRY IN LEPTOSPIROSIS
Journal Title: Journal of IMAB - Annual Proceeding (Scientific Papers) - Year 2008, Vol 14, Issue 1
Abstract
Differential count of leucocytes and six lymphocyte populations and subpopulations were investigated by flow cytometry in fourteen cases with leptospirosis. Marked granulocytosis and lymphopenia were found in 100%. The percentage of the monocytes was significantly decreased (mean 6,65%; 0,7 to 14,0%; sd 5,49). Immunophenotypization of lymphocyte populations and subpopulations by flow cytometry was revealed prevalent tendencies for decreasing of the number of total T-lymphocytes, T-helpers, T-suppressors, T-helpers/T-suppressors index; increasing of the number of the activated T-lymphocytes, subpopulation of NK cells (CD3-/ CD16+56+), and B-lymphocyte. These data are suggested that cell-mediated immunity plays a role in later stages of the diseases.
Authors and Affiliations
Galya Gancheva, Maria Atanasova, Tzvetan Lukanov, Penka Ilieva
Keywords
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- EP ID EP157259
- DOI 10.5272/jimab.14-1-2010.3
- Views 82
- Downloads 0
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