Formulation and Charcterization of Lake Color Obtained From Red Cabbage
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2016, Vol 4, Issue 1
Abstract
Colorants are mainly used to impart a distinctive appearance to the pharmaceutical dosage forms. The present study was carried out to develop aluminium lake color of a dye obtained from red cabbageusing different adsorbent (s) (Aluminium oxide or aluminium hydroxide or combination of both) in different ratio by simply mixing them to get dye adsorbed onto the surface of adsorbent.Batch Mode studies were carried out for 60 minutes. Aluminiumhydroxide at a concentration level of 30% w/v found to be the choice of adsorbent after optimization because maximum adsorption of dye from reaction mixture after 60 minutes and maximum % yield.After optimization of adsorbent the effect of pH and temperature also studied by formulating lake by varying these two parameters. It was observed that a higher temperature (50oC) and a slight acidic pH (6) favor the adsorption. The lake then characterized for various physicochemical properties like angle of repose, Carr’s index, hausner’s ratio, loss on drying, particle size
Authors and Affiliations
Shivali Singla| SMS Medical College, Jaipur, Rajasthan,India, Mukul Mathur| SMS Medical College, Jaipur, Rajasthan,India, Chetan Singh Chauhan| BN Institute of Pharmaceutical Sciences, Udaipur, Rajasthan,India, Sachin Goyal| Pacific College of Pharmacy, Udaipur, Rajasthan,India, M. Junaid| Postdoctoral Fellow, Dr. Imsampen’s Lab, Cohn BD 547, 1735 W Harrison,Rush University Medical Center, Chicago, IL 60612
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