FORMULATION AND DEVELOPMENT OF KETOPROFEN BILAYER TABLETS
Journal Title: International Journal of Drug Regulatory Affairs - Year 2017, Vol 5, Issue 4
Abstract
Aim of present research work was formulation and development of bilayer tablets of Ketoprofen to reduce the side effects of Ketoprofen and to improve the therapeutic benefits and patients’ compliance to treatment. Bi-layer tablets of Ketoprofen were prepared by direct compression technique using excipients like MCC, superdisintegrant, aspartame, colour agent were mixed properly shifted from sieve no 40. Before compression; add talc magnesium stearate mixed it well. Formulations with optimal properties have been selected to obtain bi-layer tablets of adequate quality. The in vitro dissolution study of the prepared bilayer tablets showed a controlled release of active drugs over a period of 24 hours. Keywords
Authors and Affiliations
Nagesh D R, Rakesh Kumar Jat, Ahmed Syed Mansoor
Keywords
Related Articles
- EP ID EP329097
- DOI 10.22270/ijdra.v5i4.207
- Views 88
- Downloads 0
REGULATORY REQUIREMENTS & MARKETING AUTHORIZATION OF GENERIC DRUGS IN SINGAPORE & THAILAND
The availability of generic medication is an important issue in the ASEAN region. The regulatory requirements of various countries vary from each other. Therefore, it is challenge for the companies to get drug approved f...
CRITICAL SURVEY ON THE GUIDELINES UNDER RECOMMENDATION OF CHILD RESISTANT PACKAGING FOR PHARMACEUTICAL PRODUCTS
Child resistant packaging is an integral part of packaging industry. In order to reduce the risk of poisoning in children due to accidental ingestion of hazardous chemicals like over - the - counter (OTC) medications, ho...
RISK DRIVERS OF FALSIFIED AND SUB-STANDARD MEDICINES IN EAST AFRICA: PERCEPTIONS AND PRACTICES OF PHARMACEUTICAL DRUG FACILITY OWNERS/EMPLOYEES
An interview survey was conducted among drug shop owners to investigate the access to and perception of counterfeit medication along transport corridors of East Africa spanning Kenya, Tanzania, Uganda and Democratic Repu...
INTERNATIONAL CONFERENCE ON HARMONISATION: AN OVERVIEW
The International Conference on Harmonisation (ICH) is a project that makes together the regulatory bodies of Europe, Japan and the United States and professionals from the pharmaceutical domain in the three areas to dis...
REGULATORY STRATEGY FOR REGISTRATION OF COMBINATION PRODUCTS TO US-FDA
In pharmaceutical industry all the healthcare products are categorized into Drugs, Devices, and biologics and they are regulated by their respective departments of the regulatory authorities. Due to more and more develop...