FORMULATION AND EVALUATION OF TOPICAL MICROSPONGE BASED GEL OF TURMERIC
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2018, Vol 8, Issue
Abstract
A drug delivery system enables the introduction of a therapeutic substance in the body and improves its efficacy and safety by controlling the rate, time and place of release of drug in the body .One of these includes topical preparations. These are used for localized effect at the site of their application [3, 4] A new method approached in TDDS is microsponge. Microsponge drug delivery system is a patented, higher cross linked porous, polymeric microsponge that can entrap wide range of activities and release them with desired rate [3, 4] . With lots of synthetic and inorganic drugs used in the market for treatment of various diseases; natural drugs have also gained appreciation and still has high market demand even today. Natural drug helps by reducing toxicity and any adverse drug effects and thus adding for better pharmacological effect. Curcumin which is active ingredient obtained from the powdered dry rhizomes of the plant Curcuma longa (which is commonly called turmeric). It is widely used as a colouring agent, medicinal agent and as a spice in many food items. It also can be used for treatment for conditions ranging from flatulence, jaundice, hepatitis, pains and haemorrhage [5]. An approach is being made in combining the old tradition with the new technology to gain more appreciation in the market. This leads to the formulation of “Gel Loaded Turmeric Microsponge” as a Novel Drug Delivery.
Synthesis and Antimicrobial Evaluation of some novel 4-[4-(3-chloro-2oxo-4- substituted-phenylazetidin-1-yl)phenylamino]-1,2-dihydro-2,3-dimethyl-1- phenylpyrazole-5-one
A series of eight novel 2-Azetidinones (4a-h) have been synthesized by cyclocondensation of various Schiff bases of 4-[(4-aminophenyl)amino]- 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one with chloroacetyl chloride...
FORMULATION AND EVALUATION OF HERBAL BASED ANTI MICROBIAL CREAM USING COW GHEE AS BASE
Abstract Essential oils like eucalyptus and neem are well known for its anti microbial activity. The aim of this study is to evaluate the anti-bacterial activity of two essential oils (eucalyptus oil,neem oil)by incorpor...
FUNCTIONAL OUTCOME OF FEMORAL NECK FRACTURE TREATED BY BIPOLAR HEMIARTHOPLASTY
Abstract To evaluate outcome of neck fracture of the femur grade III and IV when treated by Bipolar hemiarthoplasty in elderly. Total 42 elderly cases were incorporated in study having neck fracture of femur with grade I...
PHARMACOVIGILANCE PROGRAMME IN INDIA PRESENT CIRCUMSTANCE AND ITS PERSPECTIVES
Adverse drug reaction (ADR) is defined as any response to a drug which is harmful and unintended, and which occurs at doses normally used in man for prophylaxis, diagnosis, or therapy of disease, or for the modification...
CHARACTERIZATION AND EVALUATION OF ANTIOXIDANT ACTIVITY OF OCIMUM CANUM LEAVES AND ITS EFFECIENCY ON SCHISTOSOMA MANSONI LARVAL STAGE
Schistosomiasis is the most endemic disease caused by the genus Schistosoma. Its control is dependent on killing the worm itself or one of its larval stages. The objective of this study is to determine the total phenolic...