FORMULATION AND EVALUATION OF TOPICAL MICROSPONGE BASED GEL OF TURMERIC
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2018, Vol 8, Issue
Abstract
A drug delivery system enables the introduction of a therapeutic substance in the body and improves its efficacy and safety by controlling the rate, time and place of release of drug in the body .One of these includes topical preparations. These are used for localized effect at the site of their application [3, 4] A new method approached in TDDS is microsponge. Microsponge drug delivery system is a patented, higher cross linked porous, polymeric microsponge that can entrap wide range of activities and release them with desired rate [3, 4] . With lots of synthetic and inorganic drugs used in the market for treatment of various diseases; natural drugs have also gained appreciation and still has high market demand even today. Natural drug helps by reducing toxicity and any adverse drug effects and thus adding for better pharmacological effect. Curcumin which is active ingredient obtained from the powdered dry rhizomes of the plant Curcuma longa (which is commonly called turmeric). It is widely used as a colouring agent, medicinal agent and as a spice in many food items. It also can be used for treatment for conditions ranging from flatulence, jaundice, hepatitis, pains and haemorrhage [5]. An approach is being made in combining the old tradition with the new technology to gain more appreciation in the market. This leads to the formulation of “Gel Loaded Turmeric Microsponge” as a Novel Drug Delivery.
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF METFORMIN AND TENELIGLIPTIN IN BULK AND ITS DOSAGE FORM USING RP-HPLC
A new method was developed for simultaneous estimation of Teneligliptin and Metformin by RP-HPLC. The chromatographic conditions were successfully carried out on Inertsil ODS column C8 (4.6x250mm) of 5?m particle size, f...
DESIGN AND EVALUATION OF CLARITHROMYCIN SUSTAINED RELEASE TABLETS USING ISOLATED NATURAL POLYSACCHARIDE
The present investigation was to isolate natural polymers like tamarind seed polysaccharide, followed by formulation of clarithromycin sustained release tablets. The polymer, drug and dug excipient mixtures were subjecte...
AN OVERVIEW OF CATARACT ACTIVITY AND THEIR SCREENING METHODS
A cataract is a clouding of the lens in the eyes which leads to a decrease in vision. Cataracts often develop slowly and can affect one or both eyes. Cataracts are the cause of half of the blindness and 33% of visual imp...
FORMULATION AND EVALUATION OF DORSOLAMIDE HCL OCULAR INSERT
Matrix type of ocular insert was prepared using hydrophilic polymer PVP K 30 in different concentration by solvent casting method. The compatibility study of drug and polymer was performed by FTIR and DSC study and resul...
COMPREHENSIVE REVIEW OF IMPORTANT ANALYTICAL REAGENTS USED IN SPECTROPHOTOMETRY
Abstract An innovative and comprehensive range of chromogenic reagents or colorimetric reagents are generally used for the application in the field of spectroscopic quantitative and qualitative analysis. There are number...