FORMULATION DEVELOPMENT AND EVALUATION OF MEDICATED JELLY WITH CUMINUM CYMINUM EXTRACT AND ITS COMPARATIVE STUDY USING DIFFERENT JELLING AGENTS
Journal Title: Indo American Journal of Pharmaceutical Sciences - Year 2018, Vol 5, Issue 4
Abstract
Convenience of administration and patient compliance are gaining significant importance in the design of dosage forms. Present study was aimed to formulate and evaluate medicated Jelly of Cuminum cyminum using polymers like sodium alginate and tragacanth. Difficulty in swallowing is common among all age groups, especially in elderly and pediatrics. Physical characteristics, pH, in vitro % drug release kinetics, content uniformity, spreadability, IR spectral analysis, and stability studies were conducted. IR spectroscopic studies indicated that there were no drugexcipient interactions with tragacanth but was an interection with sodium alginate. The prepared jellies of Cuminum cyminum were found to be stable and there are no significant changes in physical appearance, pH, In vitro dissolution studies. Thus, the study confirmed that the Cuminum cyminum oral jelly can be used as a possible alternative to recently available oral formulations. Keywords: Cuminum cyminum, sodium alginate, tragacanth
FORMULATION AND EVALUATION OF CEFADROXIL MUCOADHESIVE TABLETS
Cefadroxil was formulated as mucoadhesive tablets to improve its bioavailability. Xanthan Gum, Guar Gum , Chitosan and Acritamer 940 were selected as polymers. Various formulations were prepared by using these polymers a...
FABRICATION AND EVALUATION OF FAST DISTINTEGRATING ORAL HYBRID FILMS OF NEW MOIETY OF COUMARIN
The main aim of this investigation is to develop fast disintegrating oral films of new moiety of coumarin by using Pectin and synthetic polymers. The coumarin moiety loaded oral-dispersible films were formulated by using...
STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF TIAGABINE HYDROCHLORIDE IN TABLET
A simple, rapid, economical, precise and accurate Stability indicating RP-HPLC method for estimation of Tiagabine Hydrochloride in their dosage form has been developed. A reverse phase high performance liquid chromatogra...
FORMULATION AND EVALUATION OF HERBAL ANTISEPTIC - HEMOSTATIC SOLUTION
Traditionally Used solutions for the treatment of Cuts , Open wounds ,Abrasions of skin , Incisions are only having the antiseptic ( antimicrobial ) activity but they do not stop the bleeding; hence to overcome this prob...
ANTIMICROBIAL AND CYTOTOXIC ACTIVITIES OF PLANTDERIVED ENDOPHYTIC METABOLITES FROM NORTHERN BORDER REGION, KSA.
Indigenous plants in Northern border region of Saudi Arabia are still virgins; the majority of them are still not markedly investigated for their phytoconstituents and/or their endophytic metabolites. The present work de...