Frequency of ABH Secretors/Non Secretors and Its Clinical Significance: A Cross Sectional Study in Gwalior
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 6
Abstract
The ABO blood group and secretor status of individuals is inherited independently. ABO blood group antigens are inherited by A, B & H genes and gene responsible for secretor state is Se (Se/Se & Se/se) gene. If recessive gene se/se is inherited person is non secretor. These group specific substances, ABH may be detected in most body fluid as soluble form in secretors except cerebrospinal fluid (CSF). One of the richest and most available source is saliva. Secretor status of a person can be quite useful to determine certain doubtful cases of ABO blood grouping and also has clinical significance. A total number of 1001 blood donors were randomly registered and studied for secretor/ non-secretor status in the present study. From the study, we conclude that secretors are more prevalent in our region (72.4%) and probable frequency Se and se gene was .475 and .525 while frequency of SeSe, Sese and sese allele genes was .226, .498 and .276 respectively. Secretors have an added degree of protection against the environment, particularly with respect to microorganisms and lectins. Non secretors are more prone to different varieties of auto-immune diseases and TTIs infections. Alcoholism has been associated with the Non-secretor blood type. Secretor status of an individual is also helpful to identify weaker variants of ABO group.
Authors and Affiliations
Poonam Woike, Sudha Iyengar, Dharmesh Chandra Sharma, Rajesh Gaur
Keywords
Related Articles
- EP ID EP600596
- DOI 10.9790/0853-160602116124.
- Views 63
- Downloads 0
A study of Quality of Life in Patients of HIV /AIDS Undergoing Anti-retroviral Therapy in Rajindra Hospital Patiala, Punjab
Introduction: HIV infection interferes with the immune system and increases the susceptibility of patient to many opportunistic infections. The anti-retroviral therapy (ART) that is given for the treatment of HIV infecti...
Role of Corticosteroids in Reducing Postoperative Morbidity Following Removal of Impacted Wisdom Teeth: A Comparative Study
Background: The surgical removal of impacted third molar teeth can result in considerable pain, swelling and trismus. Pain and swelling can be reduced via the glucocorticoids and with no nsteroidal anti inflammatory drug...
To Assess the Validity of Leon Williams Facial Forms and Visagism: A Photographic Study
A study was performed to re-evaluate Leon Williams theory and concept of visagism among the undergraduate dental students in our institution. 100 dental students comprising of 50 males and 50 females age group 18-30 year...
Prevalence of Diabetes in Pregnancy At A Tertiary Care Institution And Associated Perinatal Outcomes
Background: Diabetes in pregnancy has implications for the health of the mother and her baby in the immediate, short-term and long-term. Studies have shown that diabetes in pregnancy can influence maternal and neonatal o...
Study of Prevalence of HPV Genome and Detection of Cervical Abnormalities Using Liquid Based Cytology in HIV Positive Women
Background: Cervical cancer is the second most common cancer among women worldwide. Infection with the Human Immunodeficiency Virus (HIV) and its related immunosuppression are associated with an increased risk of prevale...