Frequency of ABH Secretors/Non Secretors and Its Clinical Significance: A Cross Sectional Study in Gwalior
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 6
Abstract
The ABO blood group and secretor status of individuals is inherited independently. ABO blood group antigens are inherited by A, B & H genes and gene responsible for secretor state is Se (Se/Se & Se/se) gene. If recessive gene se/se is inherited person is non secretor. These group specific substances, ABH may be detected in most body fluid as soluble form in secretors except cerebrospinal fluid (CSF). One of the richest and most available source is saliva. Secretor status of a person can be quite useful to determine certain doubtful cases of ABO blood grouping and also has clinical significance. A total number of 1001 blood donors were randomly registered and studied for secretor/ non-secretor status in the present study. From the study, we conclude that secretors are more prevalent in our region (72.4%) and probable frequency Se and se gene was .475 and .525 while frequency of SeSe, Sese and sese allele genes was .226, .498 and .276 respectively. Secretors have an added degree of protection against the environment, particularly with respect to microorganisms and lectins. Non secretors are more prone to different varieties of auto-immune diseases and TTIs infections. Alcoholism has been associated with the Non-secretor blood type. Secretor status of an individual is also helpful to identify weaker variants of ABO group.
Authors and Affiliations
Poonam Woike, Sudha Iyengar, Dharmesh Chandra Sharma, Rajesh Gaur
Keywords
Related Articles
- EP ID EP600596
- DOI 10.9790/0853-160602116124.
- Views 82
- Downloads 0
Attitudes Towards Disabled Children:- A Qualitative Study In Rural Region of Maharashtra.
.
An Original Article : Spectrum of Imaging Findings of Takayasu Arteritis With Digital Subtraction Angiography : A Prospective Study In A Tertiary Care Hospital
BACKGROUND- Angiographic demonstration of the extent of involvement of large vessels in suspected cases of Takayasu arteritis. OBJECTIVES- Our objective is to identify the spectrum of clinical manifestations, extent of a...
To Study The Effect of Pterygium Excision on Corneal Curvature And Contrast Sensitivity
Introduction: There is a high incidence of Pterygium in our country. Pterygium effects corneal curvature as well as contrast sensitivity. Hence in this study 50 patients with pterygium were taken and the effect of pteryg...
Effect of Global Postural Re- Education Method on Pulmonary Function And Chest Excursion in Moderate Chronic Obstructive Pulmonary Disease Subjects
Background: Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation, pulmonary hyperinflation with reduced muscle efficiency resulting in muscle shortening and reduced chest expansion . Stretc...
Robust Detector of Multi-Pixel Targets Using a Sequence of Images
We design and assess an algorithm to detect a multi-pixel target of an unknown spatial size, shape and position in a sequence of images in the presence of an additive Gaussian background clutter and a channel noise. The...