Frequency of HCV and HBV Co-infections in HIV Positive Patient in City of Iran: A Cross-Sectional Study
Journal Title: International Journal of TROPICAL DISEASE & Health - Year 2015, Vol 6, Issue 1
Abstract
Aims: One of the current crises of the society is prevalence rate of viral co-infection of hepatitis B and C among HIV patients.HIV, HBV, and HCV are major public health concerns. Because of shared routes of transmission, HIV-HCV coinfection and HIV-HBV coinfection are common. HIV-positive persons are at risk of being infected with HBV and HCV. Frequency of co-infection with HBV and HCV in HIV-patients is depended on the geographic regions and the type of exposure. The aim of this study was to determine the prevalence of HIV, HBV and HCV co-infection in one of the medical educational centers of Lorestan province, Iran. Study Design: This Cross-sectional One Shot Case Study Design to determine the prevalence of concurrent viral infection in the city of Khorramabad, Iran. Place and Duration of Study: Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran and Shohadaye Ashayer hospital, Khorramabad, Iran, in 2013 Methodology: This cross-sectional study was designed in 2013 in order to study the prevalence of co-infection among 500 outpatients and inpatients referring to Shohadaye Ashayer Hospital, Khorramabad, Lorestan province. The existence of specific antigen and antibody against the virus was determined by Enzyme-Linked Immunosorbent Assay. (Demographic information was extracted from the patients' medical files and frequency of three viruses was calculated according to demographics information. Results: 103 out of 500 studied serum samples were infected with HBV, HCV, and HIV viruses. Maximum infection was in the age range of more than 40 years old, which was equal to 23 patients (24.7%). 58 out of 103 samples were inpatients, 18 (9.4%) of whom were co-infected. 3 out of 103 studied samples (5.9%) who were co-infected with HIV/HBV/HCV were male. On the other hand, 4 (3.9%) male patients were infected with HIV/HBV and 4 (7.8%) male patients were co-infected with HBV/HCV. Also, 23 (22.3%) patients were co-infected with HIV/HCV; one (1.9%) was female and 22 (43.1%) were male. Conclusion: Patients who have both hepatitis B and C infections when are associated with HIV infection the disease becomes more severe. By obtain frequency, relationship was detected between hospital care of patients and prevalence of con-infection. Due to frequent injections in the hospital and taking blood and its products, inpatients were more susceptible to infection than outpatients. So, the probability of their infection with viruses was higher than outpatients. This issue is a disturbing factor in medicinal centers which should receive more attention.
Authors and Affiliations
Fatemeh Saleh, Hossein Azizi, Farnaz Kheirandish, Fariborz Rashnou, Seyed Dawood Mousavi Nasab, Fatollah Movahedi, Maryam Azizi
Keywords
Related Articles
- EP ID EP343336
- DOI 10.9734/IJTDH/2015/13282
- Views 60
- Downloads 0
Determinants of Maternal Mortality in Mezam Division in the North West Region of Cameroon: A Community-based Case Control Study
Background: Since 2008, an average of 358,000 women die annually worldwide of pregnancy-related causes. About 99% of these deaths occur in developing countries, 43% of which occur in Sub-Saharan Africa alone. In Cameroon...
Cholecystitis – Mode of First Presentation of Sickle Cell Anemia in an Adult Nigerian: A Case Report
Background: This article aimed to sensitize the healthcare providers to the possibility of late and atypical presentation of sickle cell anemia (SCA). Case Presentation: A 24 year old female university undergraduate pre...
Shiga Toxin and Non-Shiga Toxin-Producing Escherichia coli O157 from Cattle, Goats and Chickenin Ado-Ekiti, South West, Nigeria
Background: Illnesses due to contaminated food, particularly food of animal origin, are perhaps the most widespread health problem in the contemporary world. Aims: To detect Shiga toxin-producing Escherichia coli (STEC)...
Prevalence of Latent Tuberculosis Infection among Health Workers Resident in Akwa Ibom State, South-South Nigeria
Background: Tuberculosis (TB) remains a Public health problem in Nigeria and Healthcare workers (HCWs) are at risk of Latent Tuberculosis Infections (LTBI) and TB disease. There has been no available information on the p...
Malaria Diagnostic Testing among Public Health Physicians in Nigeria
Aims: Malaria is a major endemic public health problem in Nigeria and its diagnosis is often either missed or over-diagnosed. It is therefore necessary to determine the use of malaria diagnostic tests by the Community He...