Frequency, preferences and prescribing pattern of antihypertensive drugs in Out-Patient Department of a tertiary care SGM Hospital, Rewa district of Madhya Pradesh, India
Journal Title: The Indian Practitioner - Year 2016, Vol 69, Issue 78
Abstract
Aims and Objectives: The aim of study was to determine the frequency and prescribing pattern of antihypertensive drugs in Out Patient Department of a tertiary care hospital and to identify whether the pattern of prescribing is appropriate in accordance with national and international guidelines for pharmacotherapy of hypertension. Methods: This was a prescription-based survey; the prescriptions were collected randomly from OPDs of SGM Hospital as xerox copies after taking the consent of the patients. A total of 3587 prescriptions were analysed. Results: In the 3587 prescriptions a total 8144 drugs were prescribed; of these only 4.19% (342) drugs belonged to the cardiovascular group. Among the cardiovascular drugs 94.73% (324) belonged to antihypertensive and 5.26% were anti-CHF drugs. 91.35% drugs were prescribed as monotherapy and 8.64% as combination therapy. The Calcium channel blockers (CCBs) (Amlodipine 83.47%) were the most frequently prescribed antihypertensive drugs (35.49%) followed by Angiotensin-converting-enzyme inhibitors (ACEIs) 25% (Enalapril 60.49%), β-blockers 13.27% (Atenolol 69.76%), angiotensin (AT1) receptor antagonists or angiotensin receptor blockers (ARBs) 9.25% (Losartan 80.0%), combination therapy 8.64% (AT+AM / LO+HCTZ 46.42%) and diuretics 8.33% (Hydrochlorothiazide 55.55%). However over all prescribing frequency among antihypertensive drugs were as follows: Amlodipine (29.63%) ≥ Enalapril (15.12%) ≥ Ramipril (9.87%) ≥ Atenolol ≥ (9.25%) ≥ Losartan (7.40%) hydrochlorothiazide ≥ (4.63%) ≥ Es-amlodipine (4.32%) ≥ AT+AM (4.01%)= LO+HCTZ (4.01%) ≥ Frusemide (3.70%) ≥ Candesartan (1.85%) ≥ Metoprolol (1.54%) and others. Conclusions: Most of antihypertensive drugs in this study were prescribed as monotherapy. Amlodipine was most frequently prescribed antihypertensive followed by Enalapril ≥ Ramipril ≥ Atenolol ≥ and Losartan, in combination therapy AT+AM and LO+HCTZ were equally prescribed. The pattern of this study was in accordance with the National and International guidelines.
Authors and Affiliations
Prabhakar Singh, Keshav Singh, Roshani Shrivastava, Vivek Pandey, Amita Singh, Raj Bhupendra
Keywords
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