Functional dyspepsia and immune dysfunction: modern concepts of pathogenetic mechanisms of their development
Journal Title: Сучасна гастроентерологія - Year 2018, Vol 0, Issue 1
Abstract
The review presents the main modern opinions on the immunological factors of functional dyspepsia development and data on its micromorphological basis. The immune dysfunction is considered as an important factor in the pathogenesis of functional dyspepsia at different levels, the local level (in a form of duodenal eosinophilic infiltration with eosinophils’ degranulation of and mastocytosis) and general level (imbalance of cellular and humoral immunity with the predominance of pro-inflammatory cytokines). The prospects of further studying the features of immune dysfunction in the development of functional dyspepsia have been substantiated.
Authors and Affiliations
O. Yu. Gubska, T. S. Alianova
Keywords
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