Functional exocrine pancreatic insufficiency as target of pharmaceutical and surgical approaches in treatment of overweight
Journal Title: Postępy Nauk Medycznych - Year 2015, Vol 28, Issue 5
Abstract
Overweight and obesity are major health problem in today’s society, where the western diet and a sedentary lifestyle has been suggested as primary causes. Lifestyle changes, such as the introduction of a healthier diet and increased physical activity, should be considered a first step in the management of obesity. However, many patients struggle to lose weight with these types of interventions. For these patients, pharmaceutical and surgical treatments may be an option. The most commonly used pharmaceutical and surgical approaches for the management of obesity aim to induce weight loss by creating functional exocrine pancreatic insufficiency. Pancreatic enzymes are crucial for the digestion of macronutrients. Thus, by targeting these enzymes, digestion and absorption of nutrients will be reduced. Although these treatment strategies usually show good results in terms of weight loss, they are associated with nutritional and metabolic complications. It is therefor of great importance that both medical doctors and patient are well informed about the risks that come with various therapies.
Authors and Affiliations
Emelie Andersson, Lisa Månsson, Catherine Gidlund, Renate Kat, Kateryna Goncharova, Olena Prykhodko, Stefan G. Pierzynowski
Keywords
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