Fungal Profiling in Patients with Chronic Suppurative Otitis Media: A Microbiological Study
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 8
Abstract
Introduction: One of the complications of acute otitis media is chronic suppurative otitis media although the risk factors responsible for this are unclear. Development of chronic suppurative otitis media may be related to the frequent infection of the upper respiratory tract and poor socioeconomic conditions. Long term antibiotic and steroidal therapy for its treatment are assumed to suppress the resident bacterial flora with a resultant increase in fungal growth. Hence; this study was undertaken to assess the fungal growth in patients with chronic suppurative otitis media. Material and Methods: 214 clinically diagnosed patients of chronic suppurative otitis media who reported in the hospital from June 2012 to July 2014 were included in the present study. Patients presenting with tympanic perforation and ear discharge of more than 2 months were included in the study. Inoculation of the swabs of the patients was done on two sets of Sabouraud's dextrose agar slants with 0.05 mg/ml of chloramphenicol followed by incubation at 35°C and 28°C, respectively. Criteria of Lodder and Kreger-Van Rij and Rippon were used to identify the isolates based on colonial appearance, microscopic morphology in lactophenol cotton blue mount, slide culture preparation, and biochemical characters. Results: Approximately 77% of the patient showed positive culture results for fungal growth. Remaining of the subjects showed absence of any fungal growth. Majority of the patients in which fungal growth was present belonged to age group of 21 to 30 years. More than 50 % of the patients received topical ear drops while remaining 48 % were on oral anti-microbial therapy. Out of all the patients receiving topical therapy, maximum of them were receiving ciprofloxacin followed by gentamicin. Candida albicans was the most frequently found fungal spp. followed by aspergillus spp. Conclusion: Bacteria flora of the ear may get suppress by the prolonged use of antibiotics or steroidal drops which subsequently might lead to fungal growth.
Authors and Affiliations
Rajesh Kumar Yadav, Kumar Gaurav, Megha Bansal, Abhishek Jaiswal
Keywords
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