Future directions for use guanidine derivatives in veterinary medicine and agricultural production
Journal Title: Бюлетень "Ветеринарна біотехнологія" - Year 2017, Vol 30, Issue
Abstract
ntroduction. Modern veterinary medicine, animal production, biotechnology use more and more new different chemical compounds every year. А huge number of xenobiotic synthesized and put into practice over the past decade. Among them a prominent place is occupied with compounds of guanidine derivatives. Usually these substances are used in the various disinfectants and antiseptics. High bactericidal properties of polymeric guanidine derivatives as polyhexamethylene guanidine (PHMG) are not in doubt. Low chemical aggressiveness and toxicity, environmental safety are positive features of PHMG. However, a careful study of their physic-chemical and biological properties indicates that the potential scope of these substances can be much broader. The goal of the work was to analyze the potential applications of chemicals such as guanidine derivatives in various fields of veterinary medicine, agriculture and agro production. Materials and methods. Basic materials are the results of previous experimental studies and literature. Research methods are analysis, synthesis, comparison, extrapolation, generalization.Result of research and discussion. The most typical application of PHMG is disinfection and decontamination. It should be noted that PHMG much safer for humans, animals and ecosystems than other disinfectants. Numerous studies confirm that the preparation has low toxicity and chemically aggressive. It was established that great potential of PHMG can also be used for biotechnology, agriculture and other industries. In those concentrations when preparation gets into the environment, it does not pose a serious threat to biomes. The risk to the health and human life is minimal. Conclusions and prospects for further research. Guanidine derivatives are highly effective and safe disinfectants. Experiments with cell cultures open up perspectives for their use in biotechnology. In the future, it is advisable to focus on studying the properties of substances PHMG compositions of various types, differentiated features guanidine derivative effect on pro- and eukaryotic cells.
Authors and Affiliations
Andriy Lysytsya, Julia Mandygra
Keywords
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- EP ID EP270689
- DOI 10.31073/vet_biotech30-18
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