FUTURISTIC SCPOPE OF BIOMARKERS IN TUBERCULOSIS
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2015, Vol 8, Issue 4
Abstract
ABSTRACTOne of the major causes of the mortality from single infectious agent, tuberculosis (TB) is prevalent worldwide. India has the highest number of TBcases in the world. It is the leading cause of death, because of its high mortality and morbidity because of the disease. Reason lies in the emergenceof multidrug-resistant TB strains, and the HIV infection, which reactivates the latent TB making it more severe. Moreover, failure to diagnose TBearly remains one of the primary hurdles in controlling of the disease. TB is a potentially hazardous infectious disease attacks various organs, mainlyaffecting lungs. The bacteria causing TB are spread from one person to another. Tiny droplets released into the air via coughs and sneezes lead to thepassage of infection. The disease is generally diagnosed by its symptoms, radiographic methods, and sputum smear microscopy and by cultivation ofthe Mycobacterium tuberculosis, which is considered as gold standard. Current advances in molecular biology and molecular epidemiology and a betterunderstanding of drug resistance in TB have given a new horizon to its rapid diagnosis. However, the cost-effective techniques, and their requirementfor sophisticated equipment and skilled personals have excluded their implementation on a routine basis, especially in low-income countries.Keywords: Biochemical markers, Tuberculosis, Microbiological tuberculosis.
Authors and Affiliations
Preeti Sharma, Kumar Pradeep
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Objective: The objective of this study was to compare the effect of chitosan, lifestyle modification, and combination of chitosan and lifestyle modification on body mass index (BMI) in obese patients. Methods: A prospec...
ANTIHYPERTENSIVE EFFECT OF RUTIN: PHARMACOLOGICAL AND COMPUTATIONAL APPROACH
Objective: Phenolic compounds, such as flavonoids, have aroused great scientific interest due to their diverse pharmacological activities. Several studies suggested that flavonoids act as antihypertensive by inhibiting a...
PHARMACOVIGILANCE STUDY IN GERIATRIC POPULATION
Objective: Pharmacovigilance is defined as the science and activities concerned with the detection, assessment, understanding and preventionof adverse reactions to medicines. Main goal of pharmacovigilance in geriatric i...
ACTIVITY OF THE MEDICINAL PLANT PARKIA JAVANICA AGAINST NEISSERIA GONORRHOEAE MULTI DRUG RESISTANT AND OTHER CLINICAL ISOLATES
Objective: The objective of this study was to look into the in vitro activity of Parkia javanica against isolates of Neisseria gonorrhoeae. Methods: Methanolic extract of P. javanica bark (MEPJ) and organic fractionatio...