Gallium-67 Scintigraphy in the Era of Positron Emission Tomography and Computed Tomography Tertiary centre experience
Journal Title: Sultan Qaboos University Medical Journal - Year 2015, Vol 15, Issue 3
Abstract
Objectives: Although 18F-fluorodeoxyglucose positron emission tomography (PET)/computed tomography (CT) has largely replaced the use of gallium-67 (67Ga) scintigraphy in the evaluation and follow-up of lymphoma patients, 67Ga scans are still of value, particularly in countries where no PET/CT service is available. Te current study presents the experience of a tertiary care centre using 67Ga scintigraphy for the evaluation of lymphomas and infections. Methods: A retrospective review was conducted of all 67Ga scans performed between 2007 and 2011 at the Royal Hospital in Muscat, Oman. Images and reports of 67Ga scans were compared to clinical and radiological follow-up data including CT and PET/CT scans and biopsies when available. Results: A total of 74 patients were referred for 67Ga scintigraphy during this period with 12 patients excluded due to lack of follow-up data, resulting in 62 patients. Among these patients, 90 67Ga scans were performed, including 59 for lymphoma, 29 for infection and two for sarcoidosis assessment. Of the infection assessment scans, 22 were performed to assess pyrexia of unknown origin and seven for follow-up after known infections. Sensitivity and specifcity were found to be 80% and 88%, respectively, for the lymphoma assessment scans. For the infection assessment scans, sensitivity and specifcity were reported to be 80% and 100%, respectively. Conclusion: Results from this study were consistent with other reported rates of 67Ga scan sensitivity and specifcity in the evaluation of lymphomas and infections. Tis indicates that 67Ga scintigraphy is a useful tool for these types of evaluations when PET/CT services are not available.
Authors and Affiliations
Badriya Al-Suqri| Department of Nuclear Medicine, Royal Hospital, Muscat, Oman, Naima Al-Bulushi| Department of Nuclear Medicine, Royal Hospital, Muscat, Oman
Keywords
Related Articles
- EP ID EP14580
- DOI -
- Views 318
- Downloads 12
Notice of Duplicate Publication Perceived benefts of pre-clinical simulation-based training on clinical learning outcomes among Omani undergraduate nursing students
Array-based Identifcation of Copy Number Changes in a Diagnostic Setting Simultaneous gene-focused and low resolution whole human genome analysis
Objectives: Te aim of this study was to develop and validate a comparative genomic hybridisation (CGH) array that would allow simultaneous targeted analysis of a panel of disease genes and low resolution whole genome a...
Interstitial Cells of Cajal Pathology, injury and repair
Interstitial cells of cajal (ICC) are specialised cells located within the musculature of the gastrointestinal tract (GIT). Although they form only 5% of the cells in the musculature of the GIT, they play a critical ro...
Posterior Reversible Encephalopathy Syndrome in Two Omani Children with Underlying Renal Diseases
Posterior reversible encephalopathy syndrome (PRES) is a neurological condition with a combination of clinical and radiological features. Clinical symptoms include headaches, confusion, seizures, disturbed vision or an...
Icterus Neonatorum in Near-Term and Term Infants An overview
Neonatal jaundice is the yellowish discoloration of the skin and/or sclerae of newborn infants caused by tissue deposition of bilirubin. Physiological jaundice is mild, unconjugated (indirect-reacting) bilirubinaemia,...