Gallium-67 Scintigraphy in the Era of Positron Emission Tomography and Computed Tomography Tertiary centre experience
Journal Title: Sultan Qaboos University Medical Journal - Year 2015, Vol 15, Issue 3
Abstract
Objectives: Although 18F-fluorodeoxyglucose positron emission tomography (PET)/computed tomography (CT) has largely replaced the use of gallium-67 (67Ga) scintigraphy in the evaluation and follow-up of lymphoma patients, 67Ga scans are still of value, particularly in countries where no PET/CT service is available. Te current study presents the experience of a tertiary care centre using 67Ga scintigraphy for the evaluation of lymphomas and infections. Methods: A retrospective review was conducted of all 67Ga scans performed between 2007 and 2011 at the Royal Hospital in Muscat, Oman. Images and reports of 67Ga scans were compared to clinical and radiological follow-up data including CT and PET/CT scans and biopsies when available. Results: A total of 74 patients were referred for 67Ga scintigraphy during this period with 12 patients excluded due to lack of follow-up data, resulting in 62 patients. Among these patients, 90 67Ga scans were performed, including 59 for lymphoma, 29 for infection and two for sarcoidosis assessment. Of the infection assessment scans, 22 were performed to assess pyrexia of unknown origin and seven for follow-up after known infections. Sensitivity and specifcity were found to be 80% and 88%, respectively, for the lymphoma assessment scans. For the infection assessment scans, sensitivity and specifcity were reported to be 80% and 100%, respectively. Conclusion: Results from this study were consistent with other reported rates of 67Ga scan sensitivity and specifcity in the evaluation of lymphomas and infections. Tis indicates that 67Ga scintigraphy is a useful tool for these types of evaluations when PET/CT services are not available.
Authors and Affiliations
Badriya Al-Suqri| Department of Nuclear Medicine, Royal Hospital, Muscat, Oman, Naima Al-Bulushi| Department of Nuclear Medicine, Royal Hospital, Muscat, Oman
Keywords
Related Articles
- EP ID EP14580
- DOI -
- Views 286
- Downloads 12
A Study of Fertility Patterns of Ever Married Women in Oman
Objective: To examine the relation between age, education, residence and fertility rate and change in fertility rate between 994/95 and 999/2000. Methods: Te data for the study was extracted from the Oman National...
Re: Stress in the Medical Profession and its Roots in Medical School
Asymptomatic Ovarian Mucinous Cystadenoma with a Solid Mural Leiomyoma Case report and brief review
Mucinous neoplasms of the ovary may have associated benign or malignant mural nodules. A leiomyomatous mural nodule is a rare, benign lesion associated with mucinous tumors of the ovary. We report a case of a mural lei...
Effect of single mismatches at 3′–end of primers on polymerase chain reaction
Objective and Method – To investigate the effect of three different mismatches (G/T, G/A or G/G) at the 3•– end of a primer to amplify a 268 bp (base pair) region of the human •–globin gene using different anne...
Molecular Imaging Bridging Imaging and Biology