Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Ethanolic Extracts of Barleria acuminata Nees.
Journal Title: International Journal of Pharmacological Research - Year 2016, Vol 6, Issue 2
Abstract
Barleria acuminata Nees (Acanthaceae) commonly known as Vellaikurunji. It is used as one of the most important drugs in traditional system of medicine. The GC-MS analyses showed that the presence of Twenty two different phytocompounds in ethanolic extract of leaf of B. acuminata. The highest peak area of 34.13% for 9,12,15-Octadecatrienoic acid,(z,z,z)- was identified in leaf of B. acuminata. The ethanolic stem extract of B. acuminata showed that the presence of Twenty six different phytocompounds. The highest peak area of 46.73% for Piperidine,2,2,6,6-tetramethyl-. The root extract of B. acuminata showed that the presence of Twenty four different bioactive compounds. The root of B. acuminata showed Piperidine,2,2,6,6-tetramethyl- with the highest peak area of 39.58%. The present study confirmed that the presence of active compounds in different parts of B. acuminata. In future, the isolation of above mentioned bioactive compounds from the different part of B. acuminata would be useful to find out the novel drugs.
Authors and Affiliations
Karthikeyan V, Baskaran A. , Rajasekaran C. Sebastian
Keywords
Related Articles
- EP ID EP435231
- DOI 10.7439/ijpr.v6i2.2904
- Views 68
- Downloads 0
Adverse Drug Reactions to First Line Anti-Tubercular Drugs - A Pharmacovigilance Study
Introduction: Tuberculosis is one of the major health problems in India and developing countries. It is the second leading infectious cause of morbidity and mortality in the world. Objective: The present study was under...
A critical appraisal of medication package inserts
Introduction: Package Inserts (PIs) refers to officially specified document that accompanies a drug for relevant, updated and unbiased information for rational drug use based on regulatory guidelines as per section 6.2 a...
Efficacy and safety of oral vitamin D (cholecalciferol) supplement therapy in Stage I primary hypertension; a prospective, randomized, double-blind, placebo controlled, clinical trial in a tertiary care hospital in central India
Introduction: Hypertension is one of the most common cardiovascular disorders. Almost all targets in its therapy are exploited and there is a growing need to search for newer targets. Vitamin D is gaining increasing atte...
Novel therapies in the treatment of Parkinsons disease
Although various effective treatments for Parkinsons disease are available, novel therapies targeting the different pathways that lead to cell dysfunction and death are still required. Some of these pathways that have be...
Effect of Ethanolic Extract of Fragaria Vesca on serum glucose levels and body weight in diet induced obese rats
Objective: to evaluate the effect of ethanolic extract Fragaria Vesca on serum glucose levels in diet induced obese rats. Material and methods: Male Wister albino rats weighing 200- 250 gm, were divided into 3 groups of...