Gastrointestinal mucoadhesive drug delivery system: an overview
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2014, Vol 2, Issue 8
Abstract
The current article has been focused on the mucoadhesive drug delivery system. Mucoadhesive drug delivery system shows promising future in enhancing the bioavailability and specific needs by utilizing the physiological characters of both the dosage form and the mucosal lining. Gastrointestinal mucoadhesive dosage form may be designed to enable prolonged retention time at the site of absorption as well as providing a controlled rate of drug release for improved therapeutic outcome. Various sites for mucoadhesive drug delivery system are bucal cavity, nasal cavity, ocular, gastrointestinal tract, vaginal, rectal. This review article aims to provide an overview of the various aspects of mucoadhesion like mechanism and theories involved in mucoadhesion as well as to describe the most used methodologies and polymers in mucoadhesive drug delivery system.
Authors and Affiliations
Rajesh Asija*| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India, Sangeeta Asija| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India, Pankaj Vyas| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India, Raj Singh Chauhan| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India, Nitin Nama| Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India
Keywords
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