GC-MS analysis and antiacetylcholinesterase activity of the dichloromethane leaves extract of Ravenia spectabilis Lindl. (Rutaceae)
Journal Title: IOSR Journal of Applied Chemistry (IOSR-JAC) - Year 2018, Vol 11, Issue 4
Abstract
Ravenia spectabilis Lindl. is a plant that belongs to the genus Ravenia (Rutaceae). It is a tall, medium-sized shrub that occurs widely in South America, and can also be found in India, Pakistan, Bangladesh and other countries in Asia. Previous phytochemical studies reported the presence of quinolone alkaloids, pyranocoumarins, flavonoids and various bioactive terpenes in its aerial parts. Antibacterial and cytotoxic activities are also reported for extractives from this plant. Dichloromethane leaves extract of a specimen cultivated in the state of Rio de Janeiro, Brazil, was analyzed by GC-MS and led to the identification of the compounds isatin, lichexanthone and the terpenes α-spinasterone, lupeol, sitostenone and α-cadinol in its composition. Some of them are found for this time in both genus Ravenia and R. spectabilis. Dichloromethane leaves extract was also tested for acetylcholinesterase (AchE) inhibition and showed 54.4± 3.70 (0.1 mg/mL) % of activity.
Authors and Affiliations
Cristina Borges Viana, Isabelle Lemos Liesner, Roberto Carlos Campos Martins
Keywords
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- EP ID EP414028
- DOI 10.9790/5736-1104010811.
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