GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SUDANESE ERUCA SATIVA (BRASSICACEAE) FIXED OIL
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2017, Vol 3, Issue 9
Abstract
Eruca sativa seed oil was studied by GC-MS. The oil was also evaluated for antimicrobial activity. Twenty five components were detected by GC-MS analysis. Main constituents are: 13-docosenoic acid methyl ester (34.32%); (z,z)-9,12-octadecadienoic acid methyl ester(11.80%); cis-13-eicosenoic acid methyl ester(11.05%) ; 9-octadecenoic acid methyl ester (10.76%) ; hexadecanoic acid, methyl ester(6.98%) ; 9,12,15-octadecatrienoic acid methyl ester (6.41%) The antibacterial activity of the oil was evaluated via the disc diffusion bioassay against five standard pathogenic bacteria (Gram positive: Staphylococcus aureus and Bacillus subtitlis; Gram negative : Esherichia coli and Pseudomonasa aeruginosa and the fungus Candida albicans ). The oil showed excellent activity against Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli.However, it showed partial activity against Bacillus subtilis and it was inactive against the yeast Candida albicans.
Authors and Affiliations
Dr. Abdel Karim M.
Keywords
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