GC-MS ANALYSIS OF BIO-ACTIVE COMPOUNDS IN METHANOLIC EXTRACT OF ZIZIPHUS MAURITIANA FRUIT
Journal Title: International Journal of Pharmaceutical Sciences and Research (IJPSR) - Year 2019, Vol 10, Issue 6
Abstract
Present study highlights that plant as a source of medicine has been inherited and is an important component of the health care system in India. Ziziphus mauritiana fruit (Rhamnaceae), one of the medicinally important plants commonly found in subtropical countries, was chromatographically evaluated in the present work for the identification of various phytochemical compounds found in it. The phytochemical tests showed the presence of alkaloids, flavonoids, phenols, saponins, tannins in methanolic extract of Ziziphus mauritiana (MEZM). Majorly 24 compounds in 93.08% peak area were identified through spectrum matching with National Institute Standard and Technology (NIST) database. In accordance with known therapeutic effects of the identified compounds like 5-Hydroxymethyl furfural; 1, 5-Anhydroglucitrol; Polygalitol; Sedoheptulosan; D-Allose; Beta-D-Glucopyranoside Methyl; 3, 4-Altrosan; Nonanoic acid; Octanoic acid; 2-Hexyl- 2-Hexadecanoic acid; 2-Propyloctanoic acid; Molinate; Levetriracetam; Clindamycin and Maltol, the MEZM fruit’s justified a very good source of therapeutic agents for Cancer, Epilepsy, Alzheimer's disease, Parkinson disease, Amyotrophic Lateral Sclerosis (ALS), bacterial and fungal infections. Also, it is rich in compounds comprising anti-oxidant, anti-spermatogenic, anti-biotic, neuroprotective activity. Moreover, carbohydrate metabolism and total cholesterol regulatory compounds were also identified. Therefore, Z. maurtiana is found a pharmacologically important plant. Further, isolation of individual phytochemical constituents and subjecting it to the biological activity will give more pharmaceutically valuable results.
Authors and Affiliations
L. K. Dwivedi et al.
Keywords
Related Articles
- EP ID EP581472
- DOI 10.13040/IJPSR.0975-8232.10(6).2911-16
- Views 92
- Downloads 0
EVALUATION OF ANTIDIABETIC EFFICACY OF BROWN ALGA SPATOGLOSSUM ASPERUM J. AGARDH BY ALLOXAN STIMULATED HYPERGLYCEMIA ON WISTAR ALBINO RATS
The present investigation aims to evaluate the effect of methanol extract of Spatoglossum asperum for its anti-hyperglycemic activity against diabetics induced by alloxan in Wistar albino rats. Artificially diabetes was...
ASSESSMENT OF QUALITY OF LIFE IN DIALYSIS AND NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS
Quality of life is an essential measure that proves the effectiveness of health care, health level, and well-being. Kidney diseases are one of the major health problems that affect Quality of life. This study aimed to as...
THE POTENTIAL PROTECTIVE EFFECT OF ROASTED DATE PALM CAKE EXTRACTS (PHOENIX DACTYLIFERA L.) AGAINST NICKEL CHLORIDE-INDUCED INFERTILITY IN MALE MICE
The powder date palm cake is sold in coffee and confectionary shops in the central region of the Kingdom of Saudi Arabia, where it is used as a hot drink in the form of decoction. It is alleged by users in the local comm...
TEMPERATURE STRESS MEDIATED CONSEQUENCES ON PHYSIOLOGY AND SECONDARY METABOLITES OF DATURA STRAMONIUM (L.)
Datura stramonium (L.), a multipurpose plant of Himalayan regions which possess antiseptic, sedative, antidiarrhoeal properties used for treating various diseases which include treatment of ulcer, skin disorder, jaundice...
PHYTOCHEMICAL SCREENING AND IN-VITRO ANTIOXIDANT ACTIVITY OF KNEMA ATTENUATA (HOOK. F. & THOMSON) WARB STEM BARK EXTRACT
The plant Knema attenuata or Myristica attenuata (Myristicaceae) is an endemic tree species found in the Western Ghats. Traditionally, the stem bark of K. attenuata is used in folk medicine without any scientific informa...