HYDROXYAPATITE AND Zn-HYDROXYAPATITE SYNTHESIS USING CALCIUM FROM LAKE MANINJAU PENSI SHELLS AND RESISTANCE TEST ON BACTERIA
Journal Title: International Journal of Pharmaceutical Sciences and Research (IJPSR) - Year 2019, Vol 10, Issue 6
Abstract
HAp and Zn-HAp Synthesis with several concentrations of Zn (5%, 10%, 15%, and 20%) w/w using Ca precursor from Maninjau Lake pensi shells was done with the sol-gel method. XRF for three hours obtained 96.525% Ca content in the form of CaO. XRD result for the synthesized samples showed the same diffraction pattern as the standard HAp (ICSD: 154493) phase which the intensity decreases with the addition of Zn concentration. In Zn-HAp 15% and 20% which were sintered at 600 °C for two hours, it was found that the impurity peaks were TCP [Ca3(PO4)2] and [Zn3(PO4)2] on the XRD pattern. In this study, the maximum concentration of Zn substitution in the HAp structure was obtained in Zn-HAp 10%. SEM result showed that Zn-HAp 10% had a better homogeneity than Zn-HAp 15% which produced impurities. Good antibacterial properties were also shown by Zn-HAp 10% for both tests of bacteria i.e. Staphylococcus aureus and Escherichia coli.
Authors and Affiliations
N. Jamarun et al.
Keywords
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- EP ID EP581499
- DOI 10.13040/IJPSR.0975-8232.10(6).2993-97
- Views 70
- Downloads 0
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