Gender and Age Characteristics of Cardiac Remodeling in Patients with Postinfarction Cardiosclerosis, Diabetes Mellitus Type 2 and Obesity
Journal Title: Міжнародний ендокринологічний журнал - Year 2015, Vol 2, Issue 66
Abstract
The article identified gender and age characteristics of cardiac remodeling in patients with postinfarction cardiosclerosis, diabetes mellitus (DM) type 2 and obesity. To this end, we have examined 295 patients with postinfarction cardiosclerosis. Gender and age characteristics of cardiac remodeling in 215 patients with postinfarction cardiosclerosis, DM type 2 and obesity were compared with that in patients who did not have diabetes and obesity (comparison group (n = 80)). All patients with postinfarction cardiosclerosis were divided into groups depending on the presence of DM type 2 (first group (n = 68)), obesity (second group (n = 76)) and their combination (third group (n = 71)). Patients of all groups were matched by age (64.38 ± 1.08; 64.87 ± 1.98; 65.13 ± 1.43 and 63.47 ± 1.28 years, respectively). Diagnosis verification was carried out on the basis of the existing criteria. All patients underwent general clinical and instrumental examination. Echocardiographic studies were performed by the standard procedure of H. Feigenbaum on ultrasonic device RADMIR (Ultima PRO 30, Kharkiv, Ukraine). Gender analysis showed a probable increase in the sizes of the left ventricle and left atrium on the background of more significant decrease of systolic function in men with postinfarction cardiosclerosis, DM type 2 and obesity compared with women, regardless of age. Elderly patients experienced the same changes as middle-aged patients. In all patients we have detected violations in geometric adaptation, of them concentric remodeling was revealed predominantly in females, in surveyed males we have noticed more often eccentric left ventricular remodeling. Thus, in women valid factors determining the severity of left ventricular myocardium damage and the course of chronic heart failure, against previous myocardial infarction, are DM type 2, overweight and predominance of «favorable» concentric remodeling of the left ventricle with preserved systolic function. Whereas in men myocardial remodeling has a less favorable course with increased sizes of the left ventricle and left atrium on the background of more significant decrease of systolic function.
Authors and Affiliations
P. P. Kravchun
Keywords
Related Articles
- EP ID EP222652
- DOI -
- Views 71
- Downloads 0
Activation of intracellular enzyme systems under the influence of pathogenetic factors of oncogenesis in patients with type 2 diabetes mellitus
Background. It is proved that patients with diabetes mellitus (DM) have an increased risk of cancer. The main factors of oncogenesis in DM are obesity, cytokine imbalance, hyperinsulinemia (HI), hyperglycemia. These diso...
Cognitive impairment in patients with type 2 diabetes mellitus: the role of hypoglycemic therapy
The article presents data on epidemiology, risk factors, mechanisms of development, clinical features of cognitive impairment in patients with type 2 diabetes mellitus. The literature data about the dependence of the inc...
Comparison of Infertility Causes Structure in Men and Women in Tashkent and Andijan Regions of Republic of Uzbekistan According to Screening Data
The structure of the causes of infertility has been studied in 100 couples (200 people) with infertility in Tashkent and Tashkent region (50 families in each). It is found that among surveyed women in the genesis of infe...
Child’s Intellect and Iodine Deficiency: Mechanisms of Negative Impact and Ways of Prevention
The paper presents a review of scientific literature on the effect of iodine deficiency on the intellectual development of the child. The conclusion was made about the need for a mass iodine prophylaxis in the population...
Insulin resistance, its association with diastolic left ventricular disease and aorta elasticity in hypertensive patients
Background. The accepted threshold of insulin resistance value in arterial hypertension (AH) is absent, thus it is relevant to determine its degree in patients with AH, and to determine the interaction between the insuli...