Gender differences in association between metabolic syndrome and carotid intima media thickness
Journal Title: Journal of Diabetes and Metabolic Disorders - Year 2012, Vol 11, Issue 0
Abstract
Background Metabolic syndrome (Mets) is a cluster of cardiovascular risk factors which can predicts cardiovascular disease (CVD). Carotid intima-media thickness (CIMT) is known as a surrogate measure of subclinical atherosclerosis and predictor of CVD. Although, it has shown the association between Mets and CIMT, this relation regarding sex differences is limited. We aimed to find out whether gender differences in this association. Methods In this cross-sectional study, we recorded height, weight, waist circumference (WC), blood pressure, and lipid profiles. We used Mets; defined based on NCEP ATP III definition, and traditional cardiovascular risk factors; age, body mass index (BMI), WC, hyperlipidemia, and hypertension, in multivariate regression models which including;. The CIMT measurement < 0.73 or [greater than or equal to]0.73 mm was considered as low- or high risk to CVD. Results Overall, 150 subjects were enrolled to study that their ages were 36-75 years. The 47.3% of them (71 subjects) had Mets. CIMT was increased in Mets group compared non-Mets group (P = 0.001). In logistic regression analysis, a significant association was found between Mets and CIMT in women, but not in men (p = 0.002, and p = 0.364, respectively). After adjustment to age, WC, BMI, hypertension and hyperlipidemia, this association was significant just in women (p = 0.011) independent of WC, BMI, hyperlipidemia and hypertension. Conclusion Our data showed that MetS is a stronger risk factor for subclinical atherosclerosis in women than in men. So, we suggest the assessment of CIMT along with definition Mets in middleaged women could be lead to earlier detection of at risk individuals to CVD.
Authors and Affiliations
Ozra Tabatabaei-Malazy, Hossein Fakhrzadeh, Farshad Sharifi, Mojde Mirarefin, Zohre Badamchizadeh , Bagher Larijani
Keywords
Related Articles
- EP ID EP156126
- DOI -
- Views 123
- Downloads 0
Impact of self management on metabolic control indicators of diabetes patients
Introduction Patients with diabetes play an important role in management of their illness.. They should be involved in the intervention program to be able to improve their quality. This study investigated the effect of...
Development of an effective risk management system in a teaching hospital
Background Unsafe health care provision is a main cause of increased mortality rate amongst hospitalized patients all over the world. A system approach to medical error and its reduction is crucial that is defined by cl...
Red blood cell ATP/ADP & nitric oxide: The best vasodilators in diabetic patients
Background Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, or action, or both. Inspired by previous report the release...
An overview of the contribution of fatness and fitness factors, and the role of exercise, in the formation of health status for individuals who are overweight
Over the last half century there has been an epidemic of diminished health status induced by what seems as a concurrent rise in a population of individuals that are overfat. During the past few decades, the use of exerci...
Retraction: mobile phone text messaging and Telephone follow-up in type 2 diabetic patients for 3 months: a comparative study
This article (Zolfaghari M, et al., Metabolic Disorders 2012, 11:7) has been retracted as it has already been published in the Iranian Journal of Diabetes and Obesity (Zolfaghari M, et al., Iranian Journal of Diabetes an...