Geneneralised Idiopathic Acanthosis Nigricans- A Severe Presentation in a Nigerian Girl

Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 24, Issue 12

Abstract

Acanthosis nigricans is characterized by hyperpigmented and velvety verrucous plaques observed as symmetric eruptions. We report a 22 year old girl with generalized idiopathic acanthosis nigricans with no family history, who presented with hyperpigmented, hypertrophic and symmetric verrucous lesions at the flexor surfaces of the upper extremities, neck, face, trunk, back and the axillary region. Onset of symptoms started at 10 years and had gradually and steadily increased over a 12 year period. Result of the histopathologic analysis of the punch biopsy of the skin lesions was reported as acanthosis nigricans. Patient was of a normal weight and a thorough screening for internal malignancy was negative. In conclusion, Acanthosis Nigricans though rare can be severe even in benign cases.

Authors and Affiliations

C. R. Madubuko, A. N. Onunu

Keywords

Related Articles

Relationship between Glycated Hemoglobin and Serum Lipid Profile in Type 2 Diabetes Mellitus – A Case-control Study

Aims: The aim of the study is to find whether there is any relationship between glycated hemoglobin level and serum lipid profile in type 2 diabetes mellitus patients. Study Design: A total of 128 study participants were...

Benign Multicystic Omental Mesothelioma in Pregnancy: A Case Report and Review of the Literature

Benign Multicystic Peritoneal Mesothelioma (BMPM) is a very rare condition of unknown pathogenesis, that occurs mainly in women in their reproductive age (5:1 female/male ratio). The pathogenesis of BMPM is unclear and d...

Anemia Management Practice in French Hemodialysis Centers

Objective: Evaluate the hemoglobin (Hb) target values in hemodialysis (HD) patients treated with erythropoiesis-stimulating agents (ESA). Methods: Records of anemia parameters of HD patients treated during year 2012 in...

Deconstructing Medicine: The Alternative Cellular Energy Pathway

The pharmaceutical model for treating chronic illnesses has largely dominated the practice of medicine since the Flexner report of 1910. It essentially entails biochemical based endeavors to correct detectable or discern...

Methanolic Leaf Extract of Diospyros chloroxylon Modulates Hepatic Redox Profile and Cell Proliferation in Dimethylamine-treated Rats

Dimethylamine (DMA) is a toxicant commonly present in foods, air and water. Diospyros species is a group of plants being reported to contain several bioactive agents. The study was aimed at investigating the biological a...

Download PDF file
  • EP ID EP312581
  • DOI 10.9734/JAMMR/2017/38668
  • Views 64
  • Downloads 0

How To Cite

C. R. Madubuko, A. N. Onunu (2017). Geneneralised Idiopathic Acanthosis Nigricans- A Severe Presentation in a Nigerian Girl. Journal of Advances in Medicine and Medical Research, 24(12), 1-4. https://europub.co.uk/articles/-A-312581