Generation of Porous Structure from Basil Seed Mucilage via Supercritical Fluid Assisted Process for Biomedical Applications
Journal Title: International Journal of Pharmaceutical Sciences and Developmental Research - Year 2017, Vol 3, Issue 1
Abstract
Mucilage’s are plant derived natural polymer which are valuable due to their nontoxicity, low cost and nonirritating nature, with wide range of applications. In this work, extracted mucilage from basil seeds (BSM) was dried using three various drying methods including (1) laboratory oven drying (2) water substitution with organic solvent and laboratory oven drying and (3) water substitution with organic solvent and supercritical carbon dioxide (SC-CO2) gel drying process. The obtained products were characterized by SEM, BET and FTIR and were compared both qualitatively and quantitatively. The results of this study show that, using SC-CO2 assisted process, the 3-D BSM nanostructured networks were obtained with the pores size diameter about 40 nm, without any agglomeration. Furthermore, specific area of the final products was increased from 69 to 92 m2/g by SC-CO2 gel drying in compression with air gel drying. Our observations show that, the amount of solvent residual in the SC-CO2 dried product was affected by the weight of sample, CO2 addition rate and drying time.
Authors and Affiliations
Akbari Iman, Ghoreishi Seyyed Mohammad
Keywords
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- EP ID EP555624
- DOI 10.17352/ijpsdr.000014
- Views 72
- Downloads 0
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