GLOMERULAR FILTRATION RATE IN MALNOURISHED CHILDREN
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 20
Abstract
BACKGROUND Glomerular function or kidney function can be affected because of infection or wrong diet (imbalanced nutrients) which is most of the times seen in under nourished or obese children. Like many other organs, kidney also develops in early childhood, especially up to eighteen to twenty four months of life. Malnutrition also is common in six months to two years of life. So, glomerular filtration rate can be affected in this period of life. Malnutrition mostly occurs in low-and middle-income countries. Malnutrition refers to deficiencies, excesses or imbalance in a person’s energy and nutrient intake. Nutrition is one of the most important factors that determines growth and size of the human body in childhood. Malnutrition has effect both on renal growth and function of the kidneys. Kidneys serve the excretory and synthetic functions and are important for maintaining the normal homeostasis. We wanted to study the GFR in malnourished children especially who are under nourished as per World Health Organization (WHO) criteria. METHODS 72 malnourished children (WHO classification) who met the inclusion criteria were included in this study from June 2017 to May 2018 after taking approval from institutional ethics committee in the department of Paediatrics, Assam Medical College & Hospital. Detailed anthropometric measurements were taken and grading of malnutrition was done according to WHO classification. Serum creatinine was measured for each case. RESULTS Majority of children (68.06%) had severe malnutrition. GFR was normal in 35 (48.61%) cases, decreased in 33 (45.83%) cases, increases in 4 (5.56 %) cases. CONCLUSIONS From the study, we can say that approximately 45 % patients having low glomerular filtration rate are malnourished-children, who are under nourished as per World Health Organization (WHO) criteria; but differences in GFR between male and female, and between moderate and severe malnutrition were insignificant (p>0.05).
Authors and Affiliations
Hrishikesh Biswas, Pranoy Dey
Keywords
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- EP ID EP617770
- DOI 10.14260/jemds/2019/362
- Views 94
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