Glucose-lowering Potential of Cocoa Powder Intake - An Avenue for Positive Management of Diabetes Mellitus
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2016, Vol 16, Issue 2
Abstract
Diabetes mellitus (DM) is a public health problem which is increasing all over the world and various contributions to its prevention and management is crucial. Cocoa powder as a food ingredient has been discovered to have medicinal purposes most especially in the treatment of cardiovascular diseases. This study was conducted to determine the efficacy of cocoa powder on the blood glucose level, body weight, feed and water in-take of experimental normal and albino rats with DM. Sixty matured male and female albino rats with an average weight of 200 g were randomly divided into 10 groups of 6 rats which include the normal and diabetic control and 8 treatment groups. DM was induced intravenously by giving the rats a single dose of Alloxan Monohydrate (100 mg/kg body weight) and the treatments include 1-4% natural cocoa powder mixed-feed. The results showed that cocoa powder could normalize increase fasting blood glucose and water in-take as well as body weight loss caused by alloxan. The group with DM fed with 4% cocoa powder feed showed the lowest water intake (29.6±8.41 ml) as well as the lowest final fasting blood glucose level (101±3.26 mg/dl) when compared to the diabetic control group while the normal group fed with 4% cocoa powder had the lowest body weight (204±11.6 g) when compared to the normal control group. There was a significant decrease in the final feed intake of both the diabetic and normal treatment groups when compared to the normal control group. This study suggests that cocoa powder contains glucose-lowering potentials that could yield a positive result in the management of DM.
Authors and Affiliations
T. M. Olasope, G. T. Fadupin, O. O. Olubamiwa, C. O. Jayeola
Keywords
Related Articles
- EP ID EP341223
- DOI 10.9734/BJMMR/2016/24534
- Views 82
- Downloads 0
Faculty Perception and Attitude on Problem Based Learning (PBL) in Medical College from Central India
Background: PBL is an innovative teaching learning method that enhances intrinsic motivation, promotes self learning, encourages clinical reasoning, and develops long-lasting memory. It is an established leading educati...
Allergic Rhinitis in Children with Asthma: A Questionnaire Based Study in Lebanon
Introduction: Allergic rhinitis and asthma frequently coexist but has rarely been evaluated in Lebanese children. Aim: This prospective study aimed to estimate the prevalence of allergic rhinitis in asthmatic children in...
Effect of Obesity on Hormonal Profile and Semen Parameters of Male Partners of Infertile Couples in Kwara State Nigeria
Background: Infertility is a global and a public health concern in many parts of sub-Saharan Africa and obesity is gradually becoming an epidemic disease that is rapidly spreading among Africans. Male obesity has been as...
Effect of Dimethoate and Chlorpyrifos in Hepatic and Renal Function of People Belonging to Risk Groups in Iraklia Serres (N. Greece)
Aims: There is little evidence concerning the effects of organophosphates in the liver of healthy individuals, and the existing researches come to contradictive results. In this study, we evaluated the influence of organ...
Dearth of Haematologists in Nigeria: Unfriendly Specialty among Medical Students in Niger-Delta Region of Nigeria
Background: There is continuous rise in haematology and haemato-oncology cases in Nigeria. Unfortunately, there is inadequate number of haematologists to care for these rising cases despite the high number of medical doc...