Glycated hemoglobin in diagnosis of diabetes mellitus: Descriptive clinical study
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 4, Issue 1
Abstract
Background: Type 1 and type 2 are the two broad categories of diabetes mellitus. Insulin deficiency as a result of autoimmune immunodeficiency leads to Type 1 Diabetes. Type 2 diabetes mellitus is a heterogeneous group of disorders characterized by variable degree of insulin resistance, impaired insulin secretion and increased glucose production. Common phenotype of hyperglycemia in type 2 diabetes mellitus is caused by distinct type of genetic and metabolic defect in insulin action and / or secretion. Methodology: A hospital based prospective study was undertaken among the patients attending the outpatient department. About 133 patients who were visiting the OPD with symptoms suggestive of Diabetes were included as sample size. An informed Bilingual consent was before the study was started. Results: About 69.6% of those with abnormal HbA1c had abnormal FBS and 26.7% had normal FBS. About 30.4% of those with normal HBA1c had abnormal FBS. About 73.3% of subjects with normal FBS also had normal HbA1c.Conclusion: OGTT requires second blood sample and is therefore more costly and time consuming, bringing inconvenient in logistics and causes discomfort to the individuals
Authors and Affiliations
Vinod V Wali, Kirankumar Akka
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