GnRH Agonists: Are They Ready for Clinical Use as an Anti-adhesive Agent? A Review of the Literature
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 5, Issue 6
Abstract
GnRH agonists have been shown to intervene in the mechanism of adhesion formation in a variety of ways. Influence on the hormonal state, the inflammatory and coagulation processes contribute to the reduction of adhesion formation postoperatively. Most studies on this topic have been conducted in animal models and have indicated the possible clinical use of GnRH agonists for this purpose. The aim of this study is to investigate the literature review of the mechanisms and the possible advantages of GnRH agonists therapy in the prevention of postoperative adhesions.
Authors and Affiliations
Viktoria–Varvara Palla, Georgios Karaolanis, Ioannis Katafigiotis, Konstantinos Kontzoglou
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