Green Synthesis and Evaluation of Pharmaceutical Properties of Euphorbia umbellata (Pax) Bruyns Latex
Journal Title: Der Pharma Chemica - Year 2023, Vol 16, Issue 1
Abstract
Present work explores the synthesis and application of Silver Nanoparticles (AgNPs) using latex from Euphorbia umbellata. The study characterizes the synthesized AgNPs and evaluates their antibacterial, antifungal and larvicidal activities. Phytochemicals in the latex extract are confirmed, including proteins, saponins, phenolics, terpenoids, carbohydrates, alkaloids, steroids and cardiac glycosides. However, flavonoids, tannin and phlobatannins were absent. The characterization of AgNPs involved UV-visible spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). AgNPs exhibited antibacterial activity against Escherichia coli and Staphylococcus aureus, with increased concentration resulting in larger inhibition zones. They also displayed antifungal activity, particularly against Fusarium solani. In mortality bioassays, AgNPs showed toxicity against Drosophila melanogaster larvae, with 100% mortality in 100 µl/mL concentration within 1 hour. This research highlights the potential of Euphorbia umbellata latex derived AgNPs in various applications, including antimicrobial agents and insect pest control. Further studies may focus on characterizing specific bioactive compounds in the latex.
Authors and Affiliations
Padmini AP and Rama Bhat P
Keywords
Related Articles
- EP ID EP742487
- DOI 10.4172/0975-413X.16.1.232-238
- Views 56
- Downloads 0
Triazole Benzene Sulfonamides as Leads for Human Carbonic Anhydrase IX Inhibition: Updates on Research Progress
Introduction: Triazole moiety is considered as the most important heterocyclic therapeutic agent in medicinal chemistry. Identifying a lead compound or potential drug, with the requisite physical and biological character...
Green Synthesis and Evaluation of Pharmaceutical Properties of Euphorbia umbellata (Pax) Bruyns Latex
Present work explores the synthesis and application of Silver Nanoparticles (AgNPs) using latex from Euphorbia umbellata. The study characterizes the synthesized AgNPs and evaluates their antibacterial, antifungal and la...
Density, Ultrasonic Velocity, Viscosity and their Excess Parameters of Some Binary Liquid Mixtures of Cumene with Aromatic Hydrocarbons at 298.15 K
Density (ρ), viscosity (η) and sound velocity (u) of binary mixtures of ethyl benzene, toluene, mesitylene with cumene have been measured over the entire range of composition at temperature 298.15 K. From the experimenta...
Analytical Method Development for Dorzolamide Using UV Spectroscopy
The development and evaluation of an analytical technique for the UV spectroscopy based determination of Dorzolamide is the main focus of this study. Dorzolamide, a carbonic anhydrase inhibitor, is utilized to reduce int...
Determination and Quantification of an N-nitroso-Betaxolol in the Betaxolol Hydrochloride Active Pharmaceutical Ingredient by LC-MS/MS
A Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) method was developed for the quantification of N-nitroso-betaxolol in the betaxolol hydrochloride active pharmaceutical ingredient. Chromatographic separation w...