Green Synthesis and Evaluation of Pharmaceutical Properties of Euphorbia umbellata (Pax) Bruyns Latex
Journal Title: Der Pharma Chemica - Year 2023, Vol 16, Issue 1
Abstract
Present work explores the synthesis and application of Silver Nanoparticles (AgNPs) using latex from Euphorbia umbellata. The study characterizes the synthesized AgNPs and evaluates their antibacterial, antifungal and larvicidal activities. Phytochemicals in the latex extract are confirmed, including proteins, saponins, phenolics, terpenoids, carbohydrates, alkaloids, steroids and cardiac glycosides. However, flavonoids, tannin and phlobatannins were absent. The characterization of AgNPs involved UV-visible spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). AgNPs exhibited antibacterial activity against Escherichia coli and Staphylococcus aureus, with increased concentration resulting in larger inhibition zones. They also displayed antifungal activity, particularly against Fusarium solani. In mortality bioassays, AgNPs showed toxicity against Drosophila melanogaster larvae, with 100% mortality in 100 µl/mL concentration within 1 hour. This research highlights the potential of Euphorbia umbellata latex derived AgNPs in various applications, including antimicrobial agents and insect pest control. Further studies may focus on characterizing specific bioactive compounds in the latex.
Authors and Affiliations
Padmini AP and Rama Bhat P
Keywords
Related Articles
- EP ID EP742487
- DOI 10.4172/0975-413X.16.1.232-238
- Views 24
- Downloads 0
Determination and Quantification of an N-nitroso-Betaxolol in the Betaxolol Hydrochloride Active Pharmaceutical Ingredient by LC-MS/MS
A Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) method was developed for the quantification of N-nitroso-betaxolol in the betaxolol hydrochloride active pharmaceutical ingredient. Chromatographic separation w...
Green Synthesis and Evaluation of Pharmaceutical Properties of Euphorbia umbellata (Pax) Bruyns Latex
Present work explores the synthesis and application of Silver Nanoparticles (AgNPs) using latex from Euphorbia umbellata. The study characterizes the synthesized AgNPs and evaluates their antibacterial, antifungal and la...
Microsponge: An Innovative and Novel Strategy for Drug Delivery System
The microsponge approach has become a highly competitive and rapidly evolving technology. They are porous, highly cross-linked, polymeric microspheres that can be efficiently incorporated into topical drug delivery syste...
Recent Advancement of Phyto-Formulation in the Treatment of Neurodegenerative Diseases
Pharmacological molecular pathways during an epileptic episode and dementia were examined in the current review, which offers a helpful therapeutic approach for the treatment of neurological illnesses. The current resear...
Development and Validation of Simplified RP-HPLC Method for Quantification of Candesartan Cilexetil in Commercial Formulations
In order to produce antihypertensive effects, Candesartan Cilexetil (CC), a candesartan inactive prodrug, was quickly converted into active candesartan after absorption in the Gastrointestinal (GI) tract. This research s...