Grzyby pleśniowe i rola alergii na grzyby w przewlekłym zapaleniu błony śluzowej nosa i zatok przynosowych
Journal Title: Otolaryngologia Polska - Year 2009, Vol 63, Issue 3
Abstract
Aim: The aim of this work was to assessment the role of mould fungi and the allergy on fungi in chronic rhinosinusitis. Material and methods: We studied 30 patients with chronic rhinosinusitis with or without polyposis who underwent endoscopic nose and sinuses procedures. Clinical and immunological workup was performed for atopy in all patients. We performed CT of the sinuses, skin – prick testing on 15 fungal allergens , total IgE and fungal-specific IgE levels, eosinophilia level. Specimens were sent for mycology and histopathologic analysis for identyfi cation of fungi. Results: Fungal culture from sinuses were negative in all patients. Bacterial culture were positive in 19 cases. There was observed elevated total immunoglobulin E level in 70 % of patients. Positive skin test reactivity for fungal allergen was observed in 7 patients – 3 for Aspergillus, 2 for Alternaria and 2 for Cladosporium. Fungal specific IgE levels were below 0,35 KU/L in all patients. Nasal polyps were found in 26 patients, they were associated with asthma and aspirin intollerance. No fungal hyphae were found in histopathologic analysis. Conclusions: Our preliminary study suggest, that allergy for fungi doesn’t play a significant role in etiology and pathogenesis of the chronic rhinosinusitis with or without polyps. We did’t find any case of the allergic fungal sinusitis in our patients.
Authors and Affiliations
Małgorzata Różańska-Kudelska, Andrzej Sieśkiewicz, Barbara Południewska, Magdalena Kania, Izabela Michalczuk, Marek Rogowski
Keywords
Related Articles
- EP ID EP51739
- DOI -
- Views 113
- Downloads 0
Practical aspects of drug interactions in the pharmacotherapy in otolaryngology, or the seven cardinal sins of pharmacological treatment in otolaryngological practice
Summary Drug interactions are a growing problem in the practice of otolaryngology. The use of drugs in patients treated with polypharmacy generates the risk of adverse drug interactions which requires specialized knowled...
Zabiegi rekonstrukcyjne w wielkich guzach gruczołów ślinowych
Objective: Evaluation the outcome after extensive surgery of salivary glands tumors with simultaneous reconstruction of soft tissue and skin defect. Material: In the period 2007– 2011, surgery treatments performed in 295...
Management of recurrent sinonasal inverted papilloma in the experience of ENT Department Medical University of Warsaw
Introduction: Inverted papilloma is benign epidermal neoplasm of not recognized etiology. The lesion is estimated to represent 0.5-4% of sinonasal tumors. Generally inverted papilloma is unilateral, arises from the later...
Nowotwory złośliwe jamy ustnej i szyi w materiale Kliniki Chirurgii Szczękowo-Twarzowej w Poznaniu w okresie 2002–2004
Increasing number of malignant neoplasms of the oral cavity and facial region as well as lower age of the patients hospitalized were the interest of the authors. Material and methods. Clinical data from the years 2002–20...
Postępowanie z nawrotowym gruczolakiem wielopostaciowym ślinianek przyusznych: analiza materiału Kliniki Otolaryngologii WUM od 1988 do 2008 roku
Objectives: Treatment of patients with recurrent pleomorphic adenoma of the parotid gland is a challenge for a surgeon due to frequent problems with complete resection of all tumour foci while preserving continuity and f...