High-affinity IgE receptor gene polymorphism and allergic rhinitis in a Polish population
Journal Title: Otolaryngologia Polska - Year 2014, Vol 68, Issue 4
Abstract
Introduction: The high-affinity IgE receptor (FceRIb subunit int 2) gene polymorphism is a candidate gene in atopic diseases and is associated with atopy. The aim of this biochemical study was to investigate the association of its intronic mutation and allergic rhinitis in a Polish population. Materials and methods: 100 atopic patients and 85 controls were included in the study. Polymerase chain reaction-based analysis for FceRIb subunit int 2 gene polymorphism was used for genotyping and detection. Results: There was a difference in the frequencies of genotypes of FceRIb subunit int 2 in allergic rhinitis patients and controls. The FceRIb subunit int 2 gene polymorphism was found to be associated with allergic rhinitis in the Polish cohort. Conclusion: The results indicate that genetic factors may play an important role in the allergic rhinitis development in the investigated group.
Authors and Affiliations
Barbara Korzycka-Zaborowska, Hanna Zielińska-Bliźniewska, Jarosław Miłoński, Jurek Olszewski
Keywords
Related Articles
- EP ID EP52532
- DOI -
- Views 117
- Downloads 0
Optical rhinometry – new challenges and possibilities of rhinitis diagnostics and not only
Optical rhinometry is the only diagnostic tool in rhinitis for assessing real-time changes in nasal occlusion. It illustrates lumen changes of nasal mucosa vessels in response nonspecific/specific factors and not only. T...
Rola tomografii komputerowej i rezonansu magnetycznego w obrazowaniu i ocenie zaawansowania klinicznego przyzwojaków opuszki żyły szyjnej
SUMMARY Intrnductin- Paragangliomas are rare group of tumors originating from paraganglionic tissue. The most common site of occurrence of the head and neck paragangliomas are: carotid body, jugular foramen (glomus jugul...
Narrow band imaging in transoral laser microsurgery (TLM) in moderately advanced (T2, T3) glottic cancer
Introduction: Treatment planning in T2, T3 laryngeal carcinoma is based on clinical assessment and radiological imaging. However, to delineate precise mucosal margins for transoral laser microsurgery (TLM), a high class,...
The sonoelastography of major salivary glands in chosen pathological conditions
SUMMARY Introduction: Sonoelastography is a novel technique useful in noninvasive assessment of tissue elasticity. This method was found to date to be useful in noninvasive differentiation of benign and malignant Iesions...
Strategia w leczeniu operacyjnym przewlekłego zapalenia ucha środkowego
Abstract<br/><br/>